ID   A0A345PL15_9BACI        Unreviewed;       714 AA.
AC   A0A345PL15;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   Name=recQ {ECO:0000313|EMBL:AXI10695.1};
GN   ORFNames=CUC15_17875 {ECO:0000313|EMBL:AXI10695.1};
OS   Oceanobacillus zhaokaii.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=2052660 {ECO:0000313|EMBL:AXI10695.1, ECO:0000313|Proteomes:UP000253908};
RN   [1] {ECO:0000313|Proteomes:UP000253908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=160 {ECO:0000313|Proteomes:UP000253908};
RA   Zhu W.;
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC       {ECO:0000256|ARBA:ARBA00005446}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP024848; AXI10695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A345PL15; -.
DR   KEGG; ocn:CUC15_17875; -.
DR   OrthoDB; 9763310at2; -.
DR   Proteomes; UP000253908; Chromosome.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:InterPro.
DR   CDD; cd17920; DEXHc_RecQ; 1.
DR   CDD; cd18794; SF2_C_RecQ; 1.
DR   Gene3D; 1.10.150.80; HRDC domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR029491; Helicase_HTH.
DR   InterPro; IPR010997; HRDC-like_sf.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR044876; HRDC_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032284; RecQ_Zn-bd.
DR   InterPro; IPR018982; RQC_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR01389; recQ; 1.
DR   NCBIfam; TIGR00614; recQ_fam; 1.
DR   PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR   PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   Pfam; PF14493; HTH_40; 1.
DR   Pfam; PF16124; RecQ_Zn_bind; 1.
DR   Pfam; PF09382; RQC; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SMART; SM00956; RQC; 1.
DR   SUPFAM; SSF47819; HRDC-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AXI10695.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253908}.
FT   DOMAIN          26..195
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          213..364
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   DOMAIN          514..594
FT                   /note="HRDC"
FT                   /evidence="ECO:0000259|PROSITE:PS50967"
SQ   SEQUENCE   714 AA;  81651 MW;  36D839D66C8F591F CRC64;
     MLVKEEKILQ TYFGYETFRP GQEATIEHIL QLKNTLAVMP TGGGKSLCYQ IPGLSMDGTA
     IIISPLISLM KDQVDALNSY GIAATYINSS LTAGEQQTRL RDIASGRYKF VYVAPERFES
     GSFVNLVRKI RISLVAFDEA HCISQWGHDF RPSYRSIVPN LKKLNNIPVF VALTATATEE
     VINDIKELLH IEHVVNTGFE RDNLSFHIVK GKDKTSYIRS FLQEHPNESG IIYTATRKQA
     DTLHEQLTRR GINVAKYHAG MSENERKQSQ AAFIHDESSI MIATNAFGMG IDKSNVRFVI
     HYAMPMNIES YYQEAGRAGR DGEHSDCILL FSQQDVQLQK FLIEQSLMDD AAKQNEYHKL
     QEMINYCHTH SCLSSFILEY FDDNVTKMTC GRCSNCVELK EKEDITEEAQ MILSCVKRMG
     ERFGVGMTAK VLKGSRDKKL KEFRLDQIKT YGIMSAYTEK ELTERIHFLI AERLLATEEG
     KYPTLKLNQN SVDVLKGMRP VEMFTLTIPT SDEADYQEDL FYQLRTLRKQ IADDKGVPPY
     VLFSDVTLKE LSRYFPVTKE DMLEIKGIGE KKYEQYGEEF LTIIQNWREE NPNIKQKIRI
     TGDSSAPRTK SKTADDDRPS HIISYQMFQS GKQIKDIATI REMKKQTVEN HIFKAFQDGH
     PIAWGIFFND EEEAAVLAAR EQIEEPQLKP LREALPEGYD YTKIKAVLVK NGLM
//