ID A0A345RHF0_9RHOB Unreviewed; 438 AA.
AC A0A345RHF0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Peptidase M48 {ECO:0000313|EMBL:AXI56987.1};
GN ORFNames=C1J05_12770 {ECO:0000313|EMBL:AXI56987.1};
OS Sulfitobacter sp. JL08.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Sulfitobacter.
OX NCBI_TaxID=2070369 {ECO:0000313|EMBL:AXI56987.1, ECO:0000313|Proteomes:UP000253748};
RN [1] {ECO:0000313|EMBL:AXI56987.1, ECO:0000313|Proteomes:UP000253748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JL08 {ECO:0000313|EMBL:AXI56987.1,
RC ECO:0000313|Proteomes:UP000253748};
RA Pohlner M., Engelen B., Bunk B.;
RT "Comparative analysis of Sulfitobacter genomes from the North Sea.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003983};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU003983};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}.
CC -!- SIMILARITY: Belongs to the peptidase M48 family.
CC {ECO:0000256|RuleBase:RU003983}.
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DR EMBL; CP025815; AXI56987.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345RHF0; -.
DR KEGG; suli:C1J05_12770; -.
DR OrthoDB; 9814887at2; -.
DR Proteomes; UP000253748; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07324; M48C_Oma1-like; 1.
DR Gene3D; 3.30.2010.10; Metalloproteases ('zincins'), catalytic domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001915; Peptidase_M48.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR22726; METALLOENDOPEPTIDASE OMA1; 1.
DR PANTHER; PTHR22726:SF1; METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL; 1.
DR Pfam; PF01435; Peptidase_M48; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003983};
KW Membrane {ECO:0000256|ARBA:ARBA00022792};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU003983};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003983};
KW Reference proteome {ECO:0000313|Proteomes:UP000253748};
KW Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003983}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..438
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016692037"
FT DOMAIN 37..222
FT /note="Peptidase M48"
FT /evidence="ECO:0000259|Pfam:PF01435"
FT REPEAT 303..336
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 438 AA; 47477 MW; CA0393BBD44950E3 CRC64;
MRAQGALRLF FAFALALLVA LPAHAVQLLR DPDIEHALRK LAEPVLQAAG LNPNRVRILI
VNDSALNAFI IDSDAIFINY GLILKLDEPE MLQGVIAHEA AHIVNGHISR RMANLRNART
VSGLGMALAA VAAASGQGEA ATGLALGTSS SAQRSFLAHT RSEEASADQS GVRFLKRAGI
SPSGMLKVLQ IFEGQELLIG GRQDPYARSH PLSRDRVRAM EAFVAAFGDT STPDADRNYW
YARARGKISA FTRSPKWTFG RAKEGPTQDI TLMRQAIAHH RNSNATQAVK AIDAAIALRP
SDPFFYELKG QILLESRQIS AAVTAYKKAV DLAPKDALIL SSYGRALLAN EQYGAALQML
ENARARDFRD TRLLRDLSVA YARQGQNGMA SLVTAERYAL QGRLKDAEIH AKRASGLLPA
GSGPWQRAQD VIIAAERS
//
