ID A0A345T4F3_9ACTN Unreviewed; 948 AA.
AC A0A345T4F3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Peptidase {ECO:0000313|EMBL:AXI80858.1};
GN ORFNames=C7M71_029260 {ECO:0000313|EMBL:AXI80858.1};
OS Peterkaempfera bronchialis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Peterkaempfera.
OX NCBI_TaxID=2126346 {ECO:0000313|EMBL:AXI80858.1, ECO:0000313|Proteomes:UP000249340};
RN [1] {ECO:0000313|Proteomes:UP000249340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 106435 {ECO:0000313|Proteomes:UP000249340};
RA Batra D., Gulvik C.A.;
RT "Streptacidiphilus bronchialis DSM 106435 chromosome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the terpene synthase family.
CC {ECO:0000256|ARBA:ARBA00006333}.
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DR EMBL; CP031264; AXI80858.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345T4F3; -.
DR KEGG; stri:C7M71_029260; -.
DR OrthoDB; 4401005at2; -.
DR Proteomes; UP000249340; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd00688; ISOPREN_C2_like; 3.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR001330; PFTB_repeat.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR10559; TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR; 1.
DR PANTHER; PTHR10559:SF18; TRANSCOBALAMIN-2 PRECURSOR; 1.
DR Pfam; PF00432; Prenyltrans; 3.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249340};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 919..937
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 701..801
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
FT REGION 175..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 830..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..217
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..555
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 94072 MW; 7EC5732B59A72334 CRC64;
MGIGTTRHGS GRRGVTARLC AVLATVTALF LALVPFSTPA GADPIEKCTA TTGAIVAVDF
GHWGGPVVRG CDAHPTTGMN LLHNAGFTTV GTVHDGPGFI CRIGSGDFNG GAQYPTAAEE
SCVQTPKATA YWSYWLAPAG RNTWTYSPLG ALSDVPKPGE VEAWVFGGTD VAGTSGQPAF
SPDSVRAGGP GATPSVPPSA SPSSGPGGSP SAPGSPQPSP AVAAAARWLV GRLVDGDHLY
NEAFGAPDYA RTALLGTALA AAGGQDATLT RITAYLAAHA DDYLQPDGTS VPPDPTAVAN
LALLAEATGA DPRDFGGHDL PVDLADHVCS AAGSLGNCTA AGDFHGAFSP STQALGVLAL
ARSSVAPPAA AVARLEQLQC ADGGFSGSMI APGEFCDPEP GTTALAAMAL TLVPEAAPAL
AKATAYLADQ QQADGSYLPY TGAPGGDTWS TALGTQALLA LGRTAGAATA QRWIADRQNG
DGGFASDATG GDSDLTASAQ ALIALAGANL ATLHPADPDP SSSPSPSLSP SDTATPTGPP
SPSATSSPST PTPPAGRVPD LAKGVAYLVA PKRLLGGEYY EAFDGTGFAD FGLTIDGAFA
LAATGGNDTA LAGIVDFIDQ QRKDGTDRTV NDWTLIGTSY AGGGSIAKEA LLAQVTGRNP
RNFGGHDLIA ALDQAVCTRA AADTGCAAEG NYTHAMSVFS QSLGVIAQLR AGDASHAEAP
IGYLRSLQAE DGSWPSLIPS TGDRDVDSTA MAVMALALVP GDAAAQAVDR GVAWIAARQQ
ADGGFPGAAG DSTNSAALAI QGMSLHPEKY AGRIARARAF LAGQQNGDGG FRVASDGPQK
ESDLRASTQS VGGAVGTSFG VLLRDLTGVH STIGPGGGST DPGTGGTSGT GGIGGSGTGG
SASGGSGPLA ATGVEAQRLT LWALVLLLAG GGTVAVVRRR AATGGRRH
//
