ID A0A345UGV7_9BACT Unreviewed; 432 AA.
AC A0A345UGV7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acetyl-CoA acyltransferase {ECO:0000313|EMBL:AXI99708.1};
GN ORFNames=CYPRO_0422 {ECO:0000313|EMBL:AXI99708.1};
OS Cyclonatronum proteinivorum.
OC Bacteria; Balneolota; Balneolia; Balneolales; Cyclonatronaceae;
OC Cyclonatronum.
OX NCBI_TaxID=1457365 {ECO:0000313|EMBL:AXI99708.1, ECO:0000313|Proteomes:UP000254808};
RN [1] {ECO:0000313|EMBL:AXI99708.1, ECO:0000313|Proteomes:UP000254808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Omega {ECO:0000313|EMBL:AXI99708.1,
RC ECO:0000313|Proteomes:UP000254808};
RA Toshchakov S.V., Korzhenkov A., Samarov N.I., Kublanov I.V., Muntyan M.S.,
RA Sorokin D.Y.;
RT "Phenotypic and genomic properties of Cyclonatronum proteinivorum gen.
RT nov., sp. nov., a haloalkaliphilic bacteroidete from soda lakes possessing
RT Na+-translocating rhodopsin.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP027806; AXI99708.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345UGV7; -.
DR KEGG; cprv:CYPRO_0422; -.
DR OrthoDB; 1402717at2; -.
DR Proteomes; UP000254808; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:AXI99708.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000254808};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AXI99708.1}.
FT DOMAIN 11..280
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 289..429
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 93
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 386
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 416
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 432 AA; 46299 MW; 67674330E77143BC CRC64;
MQTDPATTPV FIDGVRTPFL KSGSDFKKML AYDLARVAIS GLLGKTGISP EAVDHTIVGT
VIQEVRTANI AREAALAAGI PDSKPAHTVT MACISSNLAL AQAADAIRLG RASAVIAGGT
ETMSDVPIRV SRRLRAKLLE AQKYKSPLEF LKILKGFKFA DLKPELPAIA EFSTNDTMGA
SCDKLAAMFG ISREDQDAFA ISSHKRAAAA WESGYYNDEV IAMQPQPGRE VVHHDNGIRG
DSSPDKLAKL RPAFVKPYGT VTAANASFLT DGASAGLVMS LNKARASGLK PMAIIKDYIF
VSQDPRHELL LGPAYATPRI LERNGLKPDD IGVYEFHEAF AGQILANLKA LSTESFMKDK
VKTSIKPFDM PMDRFNLKGG SLSIGHPFGA TGVRLVTTAA RRLHEENARY ALIAACAAGG
QGHAMLLERF DG
//
