ID A0A345WS14_9SPHN Unreviewed; 477 AA.
AC A0A345WS14;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=DM480_14195 {ECO:0000313|EMBL:AXJ96466.1};
OS Sphingomonas sp. FARSPH.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=2219696 {ECO:0000313|EMBL:AXJ96466.1, ECO:0000313|Proteomes:UP000254856};
RN [1] {ECO:0000313|EMBL:AXJ96466.1, ECO:0000313|Proteomes:UP000254856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FARSPH {ECO:0000313|EMBL:AXJ96466.1,
RC ECO:0000313|Proteomes:UP000254856};
RA Bendezu Eguis J., Morales Ruiz S., Montesinos R., Quispe Conislla J.,
RA Tataje-Lavanda L., Fernandez-Sanchez M., Fernandez-Diaz M.;
RT "Cell Culture Contaminant.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP029985; AXJ96466.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345WS14; -.
DR KEGG; sphf:DM480_14195; -.
DR OrthoDB; 9812260at2; -.
DR Proteomes; UP000254856; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR007895; MASE1.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF05231; MASE1; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000254856};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 345..477
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 477 AA; 50819 MW; EA40A077FFF45B6A CRC64;
MANQNRPAAH AADATRLWLL AASLYFVSAS AMIHLTSNGR DIATIWPANA VLLALLLVDG
KPRWLTILSA GFIANVAANL ITRDTIAGPL LYSAANVIEV AIAARLICPA RTIDGLLQSP
GATLRFIGTA GVIAPCVSGL VGAATAFLVF GEAIGSSFSI WALSDGLGLL VFTPVLLATF
RGEFVACFRS KTWRLRLETF TLLTFTALVA YGVFFVADRP LLFLLFPPIM LTTFRTGRLG
TKAAVVIVAV IGGIATMYTR GPIAMLAEGP VGQAHLFQAF LAILLLTALP VAAEVTKRAR
ITAALAEHDK EMMEKAITDP LTGLFNRAGF DLVVGHQFHR RDETQQLSVI AVDLDHFKSI
NDRWGHQAGD RALCHLAHIL TAQVRSNDVI GRLGGDEFMI LLPGSDLDQA HVIGQRIGAA
ARREPLAFDE TAVTMLSLSV GVAAARPSES FADLAHRADQ ALYAAKAAGR NAVRLAS
//
