ID   A0A345XW04_9ACTN        Unreviewed;      1016 AA.
AC   A0A345XW04;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Topoisomerase II {ECO:0000313|EMBL:AXK35820.1};
GN   ORFNames=DVA86_27510 {ECO:0000313|EMBL:AXK35820.1};
OS   Streptomyces armeniacus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=83291 {ECO:0000313|EMBL:AXK35820.1, ECO:0000313|Proteomes:UP000254425};
RN   [1] {ECO:0000313|EMBL:AXK35820.1, ECO:0000313|Proteomes:UP000254425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15676 {ECO:0000313|EMBL:AXK35820.1,
RC   ECO:0000313|Proteomes:UP000254425};
RA   Labana P., Gosse J.T., Boddy C.N.;
RT   "Draft genome of the type strain Streptomyces armeniacus ATCC 15676.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP031320; AXK35820.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A345XW04; -.
DR   Proteomes; UP000254425; Chromosome.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002586; CobQ/CobB/MinD/ParA_Nub-bd_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047739; SCO5717-like_N.
DR   NCBIfam; NF041021; SCO5717_Nterm; 1.
DR   PANTHER; PTHR43384:SF14; ESX-1 SECRETION-ASSOCIATED PROTEIN ESPI; 1.
DR   PANTHER; PTHR43384; SEPTUM SITE-DETERMINING PROTEIN MIND HOMOLOG, CHLOROPLASTIC-RELATED; 1.
DR   Pfam; PF01656; CbiA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:AXK35820.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000254425}.
FT   DOMAIN          703..806
FT                   /note="CobQ/CobB/MinD/ParA nucleotide binding"
FT                   /evidence="ECO:0000259|Pfam:PF01656"
FT   REGION          1..685
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          949..1016
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..48
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..112
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..158
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        318..337
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        344..358
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..399
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        447..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        505..519
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        541..570
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        577..601
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        604..625
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        626..641
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        959..973
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        976..1016
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1016 AA;  104149 MW;  1C1ED541C7BB09E0 CRC64;
     MSSDRDEIRV GGSTPATDRL DAEAESEHET ETTGQFTIDY TPPAWYTQDS PATDGRGEPV
     APLGLDRDAS AGADAAFPSA PLPLGGEEKD ESDEAPASVD SPDTSETASG EGSSEPDGAP
     AGSETDARGA RPGASTPDGT VDSPETVRFS SASLRQEISR FRNGGEPDGP GDGADQGGTA
     AASDDLDGAG DPDPDAPDSG GSAAASHGAT ASGKAGTAAD AGPEAFPEGV TEDGADAGTK
     SPTPDSGSVP GVGGPRDAEP QDAVPQDAIP PGHVPGADRV DDAAPAGAAE GAPEPRDTPP
     AHPLSSTPQQ AAPWPAAPGS AGTPPGGLPP LPPDFQPANP QQAADAQPAP PPPGTPWLTA
     PDAAHDAAAP AVPDQRAEQA PPAAPQHGPG APVPPAGTGP AQDAPHGQPA LPAGGHGTVP
     GSAPLPPAVP QGGQGGHPEQ PGAQGQFALG QPGQQAQQAP GQQAPQTPGQ PPVQPGGYGF
     PQPGQSGAQP PAAGQGGYGY PQSFPPAQGQ HQGQGQPEAL SPAQPGGYGF PQPAQPQQPG
     QPPAQQHGGQ QHGRQPAPPQ HQQQAPGAIE PNASAQHGGS GYPQQLPPGQ GGQNPGQALQ
     PHAPNVPQAP PPQQQQPPQP QPQSQQQSPD PRRQSHSGDG SPLGYTAAVE LSSDRLLSDK
     KKPRSQNPAR GGGRFRFGGR KDDTERQRKL ELIRTPVLSC YRIAVISLKG GVGKTTTTTA
     LGSTLATERQ DKVIAIDANP DAGTLGRRVR RETGATIRDL VTAIPYLNSY MDIRRFTSQA
     PSGLEILAND VDPAVSTTFN DDDYRRVIDV LGKQYPIILT DSGTGLLYSA MRGVLDLAHQ
     LIVISTPSVD GASSASTTLD WLSAHGYGDL VQRSVTVISG VRETGKMIKV EDIVAHFQTR
     CRGVVTIPFD EHLSAGAELD LDMMRPRTRE AYFNLSAMIA EDFSRVQQEQ GLWTADGNPP
     PQLAPPLPGQ SVPGQPYVPG QGQQPYQQQP YAQQPQQPQQ PGQQQGGWPQ QPPQQP
//