ID A0A345ZNU5_9GAMM Unreviewed; 882 AA.
AC A0A345ZNU5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=DWG18_14790 {ECO:0000313|EMBL:AXK73420.1};
OS Lysobacter sp. TY2-98.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=2290922 {ECO:0000313|EMBL:AXK73420.1, ECO:0000313|Proteomes:UP000254438};
RN [1] {ECO:0000313|EMBL:AXK73420.1, ECO:0000313|Proteomes:UP000254438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TY2-98 {ECO:0000313|EMBL:AXK73420.1,
RC ECO:0000313|Proteomes:UP000254438};
RA Kim S.-G., Park A.-Y., Lee Y.-J.;
RT "Lysobacter sp. nov. isolated from a farm soil.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP031413; AXK73420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A345ZNU5; -.
DR KEGG; lyt:DWG18_14790; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000254438; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152:SF2; DRUG RESISTANCE ABC TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000254438};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 541..871
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 334..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 95496 MW; 3272BBA82FEF0339 CRC64;
MDGSRKDSGN RDLGSGGFVR VRGAREHNLK DVDVDVPRDA LVVFAGVSGS GKSSLAFGTL
YAEAQRRYFE SVAPYARRLI DQVGVPDVDA IDGLPPAVAL QQQRGVASAR STVGSVTTLS
SLVRMMYSRA GTYPRGQPML YAEDFSPNTP QGACPHCHGL GYVYDVTETA MVPDPTLSIR
DRAIASWPPA WHGQNLRDIL VTLGYDVDRP WKDLPKKDRD WILFTEETPT VPVYAGFSPA
ETRAALKKKL EPAYMGTFTG ARRYVLHTFT TTQSALMKRR VARFLQGTLC PVCKGKRLKR
EALSVTFAGF DIGELSQLSF DRLAEVLRPV AEGGAPPAAA GDADARGAAA TKRDRAKRAA
AGASAHNAAP DVHRTPAMSE EKRLAAQRIA SDLVARIGTL QNLGLDYLAM DRATPTLSPG
ELQRLRLATQ IRSNLFGVVY VLDEPTAGLH PADSEALFDA LMHLRDVGNS LFVVEHDLEM
MRRADWLVDV GPGAGERGGE VLYSGPPDAL REVASSQTAR YLFDDTPAPQ MRTPREPTGW
LELKDVHRNN LHGIGARIPL GVLTAVTGVS GSGKSSLISQ ALVELVSGHL GHEPEDDEPD
PEAGPSVVQR THGHLAGDVD AVRRLVRVDQ KPIGRTPRSN LATYTGLFDH VRKLFAATPD
ARRRRYDVGR FSFNVAKGRC ETCEGEGFVS VELLFMPSVY APCPTCHGTR YNEATLTVKW
NGRNIAEVLA LNVDEACTFF ADEPAVLRPL ETLRDIGLGY LRLGQPATEL SGGEAQRIKL
ATELQRSQRG RGLYVLDEPT TGLHAADVDR LMVHLHSLVD AGNTVVLVEH EMRVVAHSDW
VIDVGPGAGE NGGRIVACGA PDVVATSKDS RTARYLAKAL GG
//
