ID A0A346Y5D2_9ACTN Unreviewed; 742 AA.
AC A0A346Y5D2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:AXV09679.1};
GN ORFNames=DVS28_a5022 {ECO:0000313|EMBL:AXV09679.1};
OS Euzebya pacifica.
OC Bacteria; Actinomycetota; Nitriliruptoria; Euzebyales.
OX NCBI_TaxID=1608957 {ECO:0000313|EMBL:AXV09679.1, ECO:0000313|Proteomes:UP000264006};
RN [1] {ECO:0000313|EMBL:AXV09679.1, ECO:0000313|Proteomes:UP000264006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DY32-46 {ECO:0000313|EMBL:AXV09679.1,
RC ECO:0000313|Proteomes:UP000264006};
RA Xu L., Wu Y.-H., Xu X.-W.;
RT "Complete genome sequence of Euzebya sp. DY32-46 isolated from seawater of
RT Pacific Ocean.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP031165; AXV09679.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A346Y5D2; -.
DR KEGG; euz:DVS28_a5022; -.
DR OrthoDB; 3445880at2; -.
DR Proteomes; UP000264006; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000264006};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..327
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 742 AA; 76738 MW; 017D8FEBE278F56E CRC64;
MSSLLYRIGL LTSRRRGATL LLWLIGLVGL VGTVQTVGGE FVDVVTIPGT ESQAAVDFVD
ERFPEFPAST ATVVVAAEEG ESVTSLQPEV EALAEQIGSV EGVVGVADPF GPGSVSAAGD
AIRFNVAFDD VARLVPEATF EEVQATVGGV SLPGATAALG GEVAFALSEQ EPAGLSEVIG
LLVAVVVLTI TFGQLRAMGL TLASALVGVF VAIGALTVVA GVTEVPSISM TLSLMIGLAV
GIDYALFIVS RHREQVLTGM EVHESIGRAL GTAGGAVVFA GATVVIAMAG LLVVGIPFIG
LMGLSVIVAV IVAVITSVTL LPALLGFAGD RIVRVTLPGL RNRRAAAGRS SLGTRWVRAV
ARHPVVGLLA ALVVVGMLSA PLFSMETAMP TASTAPEDTD VRQSYDLIAE RFGDGFNAPL
LVVIDHEGTD RGLSAATLAD ITAAVHGLDG IVGVAPPVSN LEGDASIISV IPEGGPADRD
TVDLLDVLRH DVLDDIDAAA GTTTYVAGPT SVAIDMDDRL GSRLPLLVAF VIGLTFVVLV
IAFRSVLVPL KAAVGILLSI SAALGVVVAV FQWGWGAELL GIEAATPILS FLPILAFAIL
FGLSMDYEVF ILSRIREDYM RTGDAHESVI RGVGVTARVI TAAAAVMISV FGSFVFADSQ
PVRMIGLALA SAVLIDATLV RLVLVPSTMV LFDRANWYLP AWLDRILPHV DIEGERLLGR
LEGTDHSPAD VVTGRELPSA AG
//
