ID A0A347STZ2_9LACO Unreviewed; 448 AA.
AC A0A347STZ2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN Name=celB {ECO:0000313|EMBL:AXX65501.1};
GN ORFNames=DS830_08360 {ECO:0000313|EMBL:AXX65501.1};
OS Bombilactobacillus bombi.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Bombilactobacillus.
OX NCBI_TaxID=1303590 {ECO:0000313|EMBL:AXX65501.1, ECO:0000313|Proteomes:UP000261753};
RN [1] {ECO:0000313|EMBL:AXX65501.1, ECO:0000313|Proteomes:UP000261753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BI-2.5 {ECO:0000313|EMBL:AXX65501.1,
RC ECO:0000313|Proteomes:UP000261753};
RX PubMed=30249635; DOI=10.1073/pnas.1803880115;
RA Motta E.V., Raymann K., Moran N.A.;
RT "Glyphosate perturbs the gut microbiota of honey bees.";
RL Proc. Natl. Acad. Sci. U.S.A. 115:10305-10310(2018).
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (PTS), a major carbohydrate active -transport system, catalyzes
CC the phosphorylation of incoming sugar substrates concomitant with their
CC translocation across the cell membrane.
CC {ECO:0000256|PIRNR:PIRNR006351}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP031513; AXX65501.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A347STZ2; -.
DR KEGG; lbm:DS830_08360; -.
DR Proteomes; UP000261753; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR004501; PTS_EIIC_3.
DR InterPro; IPR004796; PTS_IIC_cello.
DR NCBIfam; TIGR00410; lacE; 1.
DR PANTHER; PTHR33989; -; 1.
DR PANTHER; PTHR33989:SF8; PERMEASE IIC COMPONENT; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR006351};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|PIRNR:PIRNR006351};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT TRANSMEM 28..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..431
FT /note="PTS EIIC type-3"
FT /evidence="ECO:0000259|PROSITE:PS51105"
SQ SEQUENCE 448 AA; 49041 MW; A06EADFE280C8637 CRC64;
MQKLFDFLNK YLLPPLNKVA NTKVVRSIMN ASLAAVPFTI VASIFLILNN LPQIFPFAAH
FFQHTILKFS AFYMLGNTMA LGSLALYYSL SVGYYYIEEY RRAGEQQLNS FTGALLSMFA
FLLTIPSISW SHGSAQAVSK TIAPNNYLVS GVSFVNGWLQ RFGGVGIFIS IITGIIAVQL
YRLCVNKNIT IKMPAGVPEG VSRSFASLIP AILVSFVMIG LDIVLGLMHT DLHNLLSAPF
GFVKNMTGSW LGMMVILLLI HLLWVVGVHG TAIVKNSFVN PILLVALSEN ANGAHNIFAG
DFINMWVFIG GAGGTLGLVL LMVFAARSDQ LKTLGKTAIL PAIFNINEPV IFGAPIVYNP
YLIVPFIVNP MVLASVAYFA IKFHLISYVT SAIAWILPVG MGAWLGTSGN LGAVIVAFLN
LFLSVIIYYP FFKLYDNNLY KQEQLHGE
//
