ID A0A347W5Y5_9HELI Unreviewed; 409 AA.
AC A0A347W5Y5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Methyltransferase domain-containing protein {ECO:0000313|EMBL:TLD92994.1};
GN ORFNames=DCO61_10680 {ECO:0000313|EMBL:MWV70444.1}, LS64_009385
GN {ECO:0000313|EMBL:TLD92994.1};
OS Helicobacter saguini.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1548018 {ECO:0000313|EMBL:TLD92994.1, ECO:0000313|Proteomes:UP000029714};
RN [1] {ECO:0000313|EMBL:TLD92994.1, ECO:0000313|Proteomes:UP000029714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 97-6194 {ECO:0000313|EMBL:TLD92994.1,
RC ECO:0000313|Proteomes:UP000029714};
RX PubMed=25428971;
RA Sheh A., Shen Z., Fox J.G.;
RT "Draft genome sequences of eight enterohepatic helicobacter species
RT isolated from both laboratory and wild rodents.";
RL Genome Announc. 2:e01218-e01214(2014).
RN [2] {ECO:0000313|EMBL:TLD92994.1, ECO:0000313|Proteomes:UP000029714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 97-6194 {ECO:0000313|EMBL:TLD92994.1,
RC ECO:0000313|Proteomes:UP000029714};
RX PubMed=27245408; DOI=.1128/IAI.00235-16;
RA Shen Z., Mannion A., Whary M.T., Muthupalani S., Sheh A., Feng Y., Gong G.,
RA Vandamme P., Holcombe H.R., Paster B.J., Fox J.G.;
RT "Helicobacter saguini, a Novel Helicobacter Isolated from Cotton-Top
RT Tamarins with Ulcerative Colitis, Has Proinflammatory Properties and
RT Induces Typhlocolitis and Dysplasia in Gnotobiotic IL-10-/- Mice.";
RL Infect. Immun. 84:2307-2316(2016).
RN [3] {ECO:0000313|EMBL:TLD92994.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MIT 97-6194 {ECO:0000313|EMBL:TLD92994.1};
RA Sheh A., Shen Z., Mannion A.J., Fox J.G.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MWV70444.1, ECO:0000313|Proteomes:UP000477070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16-048 {ECO:0000313|EMBL:MWV70444.1}, and 16-048 (F4)
RC {ECO:0000313|Proteomes:UP000477070};
RA Mannion A., Shen Z., Fox J.G.;
RT "Multi-Generational Helicobacter saguini Isolates.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TLD92994.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QBIU01000002; MWV70444.1; -; Genomic_DNA.
DR EMBL; JRMP02000016; TLD92994.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A347W5Y5; -.
DR STRING; 1548018.LS64_11940; -.
DR OrthoDB; 9815644at2; -.
DR Proteomes; UP000029714; Unassembled WGS sequence.
DR Proteomes; UP000477070; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 6.20.50.110; Methyltransferase, zinc-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013630; Methyltransf_Zn-bd_dom_put.
DR InterPro; IPR038576; Methyltransf_Zn-bd_dom_put_sf.
DR InterPro; IPR013691; MeTrfase_14.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43861:SF5; BLL5978 PROTEIN; 1.
DR PANTHER; PTHR43861; TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF08421; Methyltransf_13; 1.
DR Pfam; PF08484; Methyltransf_14; 1.
DR Pfam; PF13489; Methyltransf_23; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:TLD92994.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029714};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:TLD92994.1}.
FT DOMAIN 16..76
FT /note="Methyltransferase putative zinc binding"
FT /evidence="ECO:0000259|Pfam:PF08421"
FT DOMAIN 254..388
FT /note="C-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08484"
SQ SEQUENCE 409 AA; 46826 MW; 82DB4D1FAB0E920C CRC64;
MLSSSKGASM LEIKKCEICG STNLIEVLNL GNHPLCDDLK KVGSSEVCKE YPITILYCES
CKSAHQKYQI QKQILFPKEY HYRSKQTNDV LNGMKNLVAS VAETFGDLKN KKVLDIGCND
GSLLDIFSDF GAITFGVEPT FAALDANAKH KIFNTYFDSD IAEILKGEKF DFITFTNVFA
HIENLDNLLY SLNKIINNET IIVIENHYLG SILNSLQFDT FYHEHPRTYS LSSFEFIAKK
LNKKITKVEF PQRYGGNIRI FLGEKAKDSI ESIKLKEQNF LNEFKNMNNR IKIWQEKKGQ
EIFNLIKKFG KLHAKAFPGR AAILLKMLNL NENHLSGIYE KKDSKKIGFY APSTKIPILS
DELLFTQNHD IVLNLAWHIS GEIRQYLESN AKIHNIKIDK IIDILDKDF
//
