ID A0A347WK03_9LACT Unreviewed; 680 AA.
AC A0A347WK03;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846, ECO:0000256|RuleBase:RU363016};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU363016};
GN Name=recG {ECO:0000256|RuleBase:RU363016};
GN ORFNames=CL176_05005 {ECO:0000313|EMBL:AXY25410.1};
OS Suicoccus acidiformans.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Suicoccus.
OX NCBI_TaxID=2036206 {ECO:0000313|EMBL:AXY25410.1, ECO:0000313|Proteomes:UP000263232};
RN [1] {ECO:0000313|EMBL:AXY25410.1, ECO:0000313|Proteomes:UP000263232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZY16052 {ECO:0000313|EMBL:AXY25410.1,
RC ECO:0000313|Proteomes:UP000263232};
RA Li F.;
RT "Complete genome sequence of Oxytococcus suis strain ZY16052.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Critical role in recombination and DNA repair. Helps process
CC Holliday junction intermediates to mature products by catalyzing branch
CC migration. Has a DNA unwinding activity characteristic of a DNA
CC helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-
CC DNA). {ECO:0000256|ARBA:ARBA00024832, ECO:0000256|RuleBase:RU363016}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363016};
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504, ECO:0000256|RuleBase:RU363016}.
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DR EMBL; CP023434; AXY25410.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A347WK03; -.
DR KEGG; abae:CL176_05005; -.
DR OrthoDB; 9804325at2; -.
DR Proteomes; UP000263232; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR CDD; cd17992; DEXHc_RecG; 1.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004609; ATP-dep_DNA_helicase_RecG.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR NCBIfam; TIGR00643; recG; 1.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363016};
KW DNA damage {ECO:0000256|RuleBase:RU363016};
KW DNA recombination {ECO:0000256|RuleBase:RU363016};
KW DNA repair {ECO:0000256|RuleBase:RU363016};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU363016};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363016};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363016};
KW Reference proteome {ECO:0000313|Proteomes:UP000263232}.
FT DOMAIN 271..435
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 454..614
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 680 AA; 76998 MW; 5E9212B9FF434FEA CRC64;
MSEKSWDDSI TLLPGIGPKS AERFGELGIE TIRNLMYHFP FRYEDIQERD IKTILDQEKV
TLKGTVVTPP VVNYFGGRKS RLVFQLAVGD SDVIQVVFFN QPYLAKQIEV GDTQGVYGKW
QSDRQNLLGM KLLKAQDEGA AFDPVYHATK GLKQSMIVKA IRQAFADYST CIQDRLPAFL
NEKYRLMPLK DALYQMHFPE DDAAHHQAER KIIFDEFFFY QWRLQQASFQ QRQHTGIEVH
YDVDDLKQLI QALPYELTNA QKQAVNEICY DLLAPYPMQR MLQGDVGSGK TLVAFLALYA
TLTAGYQGAM MVPTEILAKQ HAQAFNETFA SLDLQCELLV SHMPSKEKER VLANLASGES
SVVIGTHALI QDQVQFANLG LVVIDEQHRF GVRQRHKLLS AHQKDKAINL LQMTATPIPR
SLALSIYGEM SVSTIDELPK GRQPIQTKLA KASQINVVYQ HMEEELAKGH QIYYVLPLID
QSENLADIDN VNEVYERLAQ RFPQYNIGVL HGQLDKESQT EAMECFVTGQ MQLLVATTMV
EVGVNVPNAT MIVIQSAERF GLAQLHQLRG RVGRSDLPSY CYLIGDPTTD QGKARLKIMA
ESQDGFYISQ EDMKIRGSGE IFGQAQSGIP EFHYANLLED QVILKVARKE VQQLLRHPEQ
MTEAELETLM AWSQGQMIEI
//
