ID A0A348AM45_9FIRM Unreviewed; 1847 AA.
AC A0A348AM45;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Phenyloxazoline synthase MbtB {ECO:0000313|EMBL:BBB92143.1};
DE EC=6.3.2.- {ECO:0000313|EMBL:BBB92143.1};
GN Name=mbtB_2 {ECO:0000313|EMBL:BBB92143.1};
GN ORFNames=MAMMFC1_02828 {ECO:0000313|EMBL:BBB92143.1};
OS Methylomusa anaerophila.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Methylomusa.
OX NCBI_TaxID=1930071 {ECO:0000313|EMBL:BBB92143.1, ECO:0000313|Proteomes:UP000276437};
RN [1] {ECO:0000313|EMBL:BBB92143.1, ECO:0000313|Proteomes:UP000276437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMFC1 {ECO:0000313|EMBL:BBB92143.1,
RC ECO:0000313|Proteomes:UP000276437};
RX PubMed=29458677; DOI=10.1099/ijsem.0.002635;
RA Amano N., Yamamuro A., Miyahara M., Kouzuma A., Abe T., Watanabe K.;
RT "Methylomusa anaerophila gen. nov., sp. nov., an anaerobic methanol-
RT utilizing bacterium isolated from a microbial fuel cell.";
RL Int. J. Syst. Evol. Microbiol. 68:1118-1122(2018).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; AP018449; BBB92143.1; -; Genomic_DNA.
DR KEGG; mana:MAMMFC1_02828; -.
DR OrthoDB; 9765680at2; -.
DR Proteomes; UP000276437; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR CDD; cd12114; A_NRPS_TlmIV_like; 1.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd19535; Cyc_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF15; PYOCHELIN SYNTHASE PCHF; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR Pfam; PF18563; TubC_N; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:BBB92143.1};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000276437}.
FT DOMAIN 1432..1516
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1847 AA; 206425 MW; 0105605BBD6C82BE CRC64;
MSQNTKTNPN QLLARFRREG VFLWEQNGQL CYKAPKGRLK DNDLQALKDN KTDILDLLQA
ESKPVTVTPD PESRFEPFPL TDIQSAYLLG RHNLFGYGGL SCHIYLELNY PELDPKRTEA
VWNRLILRHD MLRTTIDQKG CQRVRQSVPQ LKVAYTDTSG WEEQKAEAKL AEIREEMGHR
LYNTDHWPLF DIGVTKAHKR AVLHFSMDFL IADWASIWLL LSEFEALYEE PGRQLPDLDL
SFRDYLLAES RLRETATYSR DKDYWLRRVD TLPSAPDLPL AGQQDNSGTA RFRRRFLQLD
NHTWEGLKQR AQKLGLTPTA VVMTAYAAVI KRWSRNEKFC LNLTLLNRLP LHAQVNDIVG
DFTSVNLLAV DWCEEYSFSE QARTLQKQLF EDLDHRLFSG VEVLREIARR RGREAALMPV
VFTSAIGLVE PTAGNQRKGK VNGHGISQTP QVVIDCQAMD GLAGLQVNWD VREGVFPDRM
VDDMFDAFDE LLRSLARTDQ IWDTNEAVAL PAWQLTERQQ INAVKAPLPD QQLHRQVLAQ
ATATPDLPAV FDSEGHVTYR ELAQRAAAVA EKLKELGCVT QDRVAIVMDK CVHQVAAVLG
TLLVGAVYVP IDTKQPELRR LAMLEQASVR FVLTCSITPM QWPDKLKIIE ADKLKPYRGN
ITIAGGNPDL PAYIIYTSGS TGQPKGVVIS HRAAANTIAD INRRFNINRG DRVLGLAQLS
FDLSVYDIFG PLSVGGALVY PNAGRLTDPS HWAELMAQQE VTVWNSVPAL MQMLVAYLNS
EQKITLPQLR LALLSGDWIP LTLPDMLVRR LPAVQVISLG GATEASIWSI YHIYKGLKAD
WRSIPYGRPL ANQEFRVLDA QLRACPVWVA GELYITGCGL AEGYWGDNKI TQERFFLHPV
DGQRLYRTGD LGRYTPGGEI EFLGREDNQV KIKGHRIELG EIEATLLKHP AVAAAGVVVD
GSGDDKALFA VVETAHRKER NPDEQKTEFD RLVNGIDEQA DVEAAGLSRE EVDLAAANLE
KAVLHSMLQA LLKAGLFADD NDEKHSEKHS HSMEEILKKD EIVPAFHWLV RRWLAMLTEA
GLLLEHPPQH FSCPRKPDGK EVNEYWQAAE ASWVAKISST GFIAYVRSNA EKLPQLLNGQ
QDPVSLLFPE GRFDHVRALY FDHVMANYLN HCICTLLKRI AGNHSGKPLR ILEIGAGTGA
TTERVLKSLE GFNVDYLFTD VTAFFIPGAK SSLGQFPGIR FGIFDVDEDY RTQGLAPNSF
DIVLAAGVLE NARDIPASMN RLKELICPGG WLVFTEPTKE HAWILASQAF MMTEPGDGLR
VDISYLDRDG WMRLLKEYGD EPVLSLPAAN HKLSSLGVHL FAKRFKEDWL PVSVPELTDF
LALRLPSHML PSQLQIADAL PLTGNGKLDR HELAKWRPKP IIENSAIEMD EKSSDLLEAQ
LAKLWAEALG IPGIGRLQSF YDHGADSLIM AQVAGKLREK CAADPSPREI PYDALLRQML
NYPTVAALAE FIRFYSQAAG RTPDALLPEL RSTSGNAVVT AYGGGGTGPL RVVFHAGLGT
MNSFHLLLEH FKLHNIGPVI GITVADPETY CEFEPSGLIE QIADDYARCL WASGHTQMQL
IGYSLGGFIA VEVARRLVEQ GLHVSDLVLI DSHPVLFDVD DDLVIELLFI PNLHITLEQA
GFGGVDSADL VRGLLHIFES NNKSVPKGSS CTIGGDEGLD KVGKLFRRLA SLSMRERFKA
YSDAVAKITG EQMPVEMAEG LYKVYRQSFK AARFTPPPYM GNIRFLLALE PFSILPDTAE
MTLDFWREVC LDEFEVTEIR GNHLSCIEEE PNATNLAKLI SAPLIKN
//
