ID A0A348HDB5_9GAMM Unreviewed; 379 AA.
AC A0A348HDB5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:BBG29617.1};
GN ORFNames=ZBT109_0841 {ECO:0000313|EMBL:BBG29617.1};
OS Zymobacter palmae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Zymobacter group; Zymobacter.
OX NCBI_TaxID=33074 {ECO:0000313|EMBL:BBG29617.1, ECO:0000313|Proteomes:UP000267342};
RN [1] {ECO:0000313|EMBL:BBG29617.1, ECO:0000313|Proteomes:UP000267342}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAM14233 {ECO:0000313|EMBL:BBG29617.1,
RC ECO:0000313|Proteomes:UP000267342};
RA Yanase H.;
RT "Zymobacter palmae IAM14233 (=T109) whole genome analysis.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AP018933; BBG29617.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A348HDB5; -.
DR STRING; 1123510.GCA_000620025_01604; -.
DR KEGG; zpl:ZBT109_0841; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000267342; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF24; MULTIDRUG RESISTANCE EFFLUX PUMP; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267342};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..97
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 156..294
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 295..339
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 185..212
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 379 AA; 41642 MW; 237D94A1CB65D48F CRC64;
MHALTRTWLK RFIITLVVFI LLVAGMFMLV SWLQSGRFHQ STDNAYVRAD SVSLRSEVTA
RVLDVPVIHN QQVKAGDVLV VLDPTDYQRQ LEKAIAALDE AKASSVEAAR NIELQRATIT
QYNAQLASDT ARDEQARVSL ARIQELFDKG AVSRQRLDDM QADYDVAHAA VRAERAAIIS
AHRSLELREA SLERARATIA EAQAQVDYAR HQLTKTRIMA PTDGVIGNVS VEKGTLAQPS
QTLMTLVPVH SLYIVANYKE TQITRMRIGQ PVEIRADAYP DIRFTGQVES LAPATGSAFS
LLPVDNATGN FNKIVQRVPV RIRLTGPLDK LNLLQVGLSV EPSVDTHDLG GNTLYVAPAL
RTTVDEVSTS TTADNANHS
//
