ID   A0A363RSP1_9BURK        Unreviewed;       474 AA.
AC   A0A363RSP1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Threonine synthase {ECO:0000313|EMBL:PWB20398.1};
GN   ORFNames=DCO45_05020 {ECO:0000313|EMBL:PWB20398.1};
OS   Comamonas sp. JNW.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Comamonas.
OX   NCBI_TaxID=2170731 {ECO:0000313|EMBL:PWB20398.1, ECO:0000313|Proteomes:UP000251772};
RN   [1] {ECO:0000313|EMBL:PWB20398.1, ECO:0000313|Proteomes:UP000251772}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JNW {ECO:0000313|EMBL:PWB20398.1,
RC   ECO:0000313|Proteomes:UP000251772};
RA   Go L.Y., Mitchell J.A.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR604450-51};
CC   -!- SIMILARITY: Belongs to the threonine synthase family.
CC       {ECO:0000256|ARBA:ARBA00005517}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWB20398.1}.
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DR   EMBL; QETI01000002; PWB20398.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A363RSP1; -.
DR   OrthoDB; 9763107at2; -.
DR   Proteomes; UP000251772; Unassembled WGS sequence.
DR   CDD; cd01560; Thr-synth_2; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR   InterPro; IPR029144; Thr_synth_N.
DR   InterPro; IPR037158; Thr_synth_N_sf.
DR   InterPro; IPR004450; Thr_synthase-like.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   NCBIfam; TIGR00260; thrC; 1.
DR   PANTHER; PTHR42690; THREONINE SYNTHASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR42690:SF1; THREONINE SYNTHASE-LIKE 2; 1.
DR   Pfam; PF00291; PALP; 1.
DR   Pfam; PF14821; Thr_synth_N; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR604450-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000251772}.
FT   DOMAIN          3..83
FT                   /note="Threonine synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14821"
FT   DOMAIN          99..336
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
FT   MOD_RES         117
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ   SEQUENCE   474 AA;  52172 MW;  85184BEFF11B77AF CRC64;
     MLYLSTRGHA EQKRFCDILL EGLAPDGGLY MPVHYPQIDD AKLTALRETL KSKGYAALAF
     EILSLYIDDI PADDLRALCN KTYTEAVFGT AAIVPVRQLE GQLMIEALSN GPTLAFKDMA
     MQLLGNLFEY ELARRGEELN ILGATSGDTG SAAEYAMRGK KGVRVFMTSP HGRMSPFQQA
     QMFSLQDENI HNIAIEGVFD DCQDIVKAVS NDHAFKAQYK IGTVNSINWA RLLAQVVYYF
     AGYLQATSQN SEKVSFTVPS GNFGNVCAGH VARQMGLPIA KLVVATNEND VLDEFFRTGV
     YQVRGAAHTF ETSSPSMDIS KASNFERFVF DLVGRDGARL QQLFAQGVAQ EGRFDLQADP
     AFQDAAGRYG FVSGKSTHAD RLATIQDTFQ RLGQMIDTHT ADGVKVAREH LGAEPMIVLE
     TALPIKFAAT IEEALGRTPE RPAKFDGIED LPKRVVVMPA DVDQVKTYIK DHCR
//