ID A0A364L7D3_9EURO Unreviewed; 641 AA.
AC A0A364L7D3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Alpha-actinin {ECO:0008006|Google:ProtNLM};
GN ORFNames=BHQ10_007737 {ECO:0000313|EMBL:RAO71725.1};
OS Talaromyces amestolkiae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=1196081 {ECO:0000313|EMBL:RAO71725.1, ECO:0000313|Proteomes:UP000249363};
RN [1] {ECO:0000313|EMBL:RAO71725.1, ECO:0000313|Proteomes:UP000249363}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIB {ECO:0000313|EMBL:RAO71725.1,
RC ECO:0000313|Proteomes:UP000249363};
RX PubMed=28649280; DOI=10.1186/s13068-017-0844-7;
RA de Eugenio L.I., Mendez-Liter J.A., Nieto-Dominguez M., Alonso L.,
RA Gil-Munoz J., Barriuso J., Prieto A., Martinez M.J.;
RT "Differential ?-glucosidase expression as a function of carbon source
RT availability in Talaromyces amestolkiae: a genomic and proteomic
RT approach.";
RL Biotechnol. Biofuels 10:161-161(2017).
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAO71725.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MIKG01000016; RAO71725.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A364L7D3; -.
DR STRING; 1196081.A0A364L7D3; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000249363; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000249363};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 10..115
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 124..230
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 484..519
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 641 AA; 73456 MW; 92872596F3F49F44 CRC64;
MLMVEKQWIL VQQKTFTKWL NNKLKVRNLA ISDLTQDLSD GVNLIHLLEI LGDESLGRYA
SKPKLRVQKF ENVNKGLDFI KLRGIQMTNI GAGDIVDGNQ KIILGLIWTL ISKFTISDIS
SEGMSAKEGL LLWCQRKTAC YPEVEVRDFS ASWNDGLAFC ALLDIHRPDL IDFDSLDKND
HRGNMQLAFD IAANEIGIPD LLDVEDVCDV DKPDERSLMT YIAYWFHAFS QLEKVENAGR
RVEKFVSNMQ GAWEMQSSYE KRMKELLAQI ANQRAEWQGA SFEGTYTDAK VQLAEFSHYK
RNQKRKWVAE KSDLAALLGN IKTKLSTYRL RPYEPPADLS LDRCDRDWEG LMQEEQGRSQ
LINETIRDIK NKLRRSFADK ANDFALTLKT LTLAISGLEG DVEDQLTHVK RLNDNLPPLD
AFLETIADLE EQCVEANIDE NDYTTYTLDE LSYELGLVKS SVAKKLAFLE NQMVARNMTN
LTPIQLEEFE SVFRHFDRDG SNTLQEIEFS AALASLGLVY DEEEMHEVFL ETCGRNSTVS
FEQFIRFMVS VTEDQNTAEQ VFQSFREVAD GKPYVTELDL RHSLIPDELI DNLLESMPKH
EGPDLLEDRD LPKYDYITFM EKMMDNQGTS EDTKRSLNGG H
//
