ID A0A364NH48_9PLEO Unreviewed; 3505 AA.
AC A0A364NH48;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Vacuolar protein sorting-associated protein 13 {ECO:0000313|EMBL:RAR16590.1};
GN ORFNames=DDE83_000159 {ECO:0000313|EMBL:RAR16590.1};
OS Stemphylium lycopersici.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Stemphylium.
OX NCBI_TaxID=183478 {ECO:0000313|EMBL:RAR16590.1, ECO:0000313|Proteomes:UP000249619};
RN [1] {ECO:0000313|Proteomes:UP000249619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIDEFI 213 {ECO:0000313|Proteomes:UP000249619};
RA Medina R., Franco M.E.E., Lucentini C.G., Saparrat M.C.N., Balatti P.A.;
RT "Draft genome sequence of Stemphylium lycopersici strain CIDEFI 213.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RAR16590.1}.
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DR EMBL; QGDH01000002; RAR16590.1; -; Genomic_DNA.
DR STRING; 183478.A0A364NH48; -.
DR Proteomes; UP000249619; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR021836; DUF3429.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF11911; DUF3429; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249619};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 3353..3373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3385..3414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 3434..3453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..115
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 139..380
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 600..836
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 1972..2547
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2794..2970
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 3067..3166
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 561..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1066..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1395..1433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1582..1614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1737..1799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3222..3260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3473..3505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..591
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1403..1418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1750..1798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3232..3246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3505 AA; 392305 MW; AE5F16E8C3331F8D CRC64;
MLEGLVSTLL NRFLGMYVQN FDPKQLNVGI WSGDVKLRDL ELRREALDQL RLPLNVVQGH
LGSLTLSIPW SNLRGKPLKV NIEDVFLLAA PKEDADYDAE EEEKRAHAVK MEKLDSAELL
KERNTEGMSA EEQQKNQSFT ASLVTAIVDN VQVTVKNIHI RYEDSIADPG HPFALGLTLA
DFSAISTDEN WKPTFIQGTS ASTHKLATLG SLAVYWDTDA KLIGTGKGSQ SSDEQDIDRE
DFIEQARGMI ARGDNPDLGD HQFILKPISG RAGLEMDKTG KPDRAKMKAR LLFDELGFII
DEDQYRDALM LVDLFHYFIR HQEYKKLQPK SSPKEDPAGW FRFAGNAVLD KIHEKNRQWS
WDFFKERRDD RIRYIELFKK KKREERLNAT ETEDLDRLER KLTYEDLRFW RSLARNQLRK
ENVGVKKPPP KQTWTSWVWG SKQEEQHDDE NTQLNEQQRK ELYDAIDWDE KKAITESVDM
PREYVKLEVN MSLRTGSFTL KRDPHGQANE ILRLLFDSFS TQLLQRTDST FVKVALEGMR
LYDGTTEGSL FPQIITVKDA PPVPDDKRIE ELNDDESSMD VEGEEDEEEE KEDPFFFLTF
ENNPLDGAAD TNLTMKLKGM EFVYNPRFVV EVAKFFKPPE RHMESIGALM ETAGATVEGI
RQQTRAGLEF ALTEHKTINA QLDLQAPLII VPDSVTKKSS NCLILDAGHV SVTSELVDKE
TLRDIQAKQT QQYTDEDFRK LENLMYDRFN LKLQSTQVLI GPSIEETRAQ LDEDSSVKNY
HIVDRINIDF KIEICIVPKA SDLTKFRVSG TLPVLHASVS DSKYKNLMKL IDVAIPKFGN
DSPSKPLIEG AKGPSNLKPT SEGKAGKDPL ARSRSKSFKF AAQDHELVME EDSHSDADAD
EQFSDAPEPE DKKQRAHLHQ RNFEFKFTVD KLQGSLYRAD PEGRKSDQLL VELIAESFDL
DFYQEAFEMA ADVRLRSLAV EDHVEESTIP EFKNIITSED VSADEQKDLF SLKFVKVNKE
SPEFQTKYEG IATNLDVAVS TINLIVTRRT LLTLLDFVLD TFTNNGPPQN QQAQITDKQE
EQPIAKPPQA EPDKIRIRAE LKRIAVVLNN DGIRLATLSL SSGDVGIFLS GKTMRIGGRL
GNLSLIDDIN QGVSEESSLR QLVTIEGKNL ADFSYETYDP ETESYPGYDA AVALKTGSVK
INFLTEPFRK IMEFAVKFGK MQAIFNAARQ AAANQATQIQ QRATRFHYDI TISTPIVVFP
RMVVSDKPER DTLIANLGEI YAKNSFVPLD DSTSADTANK ISAGIRNIKL TSKLHYDSDR
SEELQLIDNV DLGFNITMVE HKPGQQRPDL EIDGSMSNIN LQLTPDQMKF ALELSRSIPA
AFATESEAID QDVQAELPNE TTEPARRMTD KSDTESVRSK DLVTSQGPEL HSDNEDKWTK
LDFVFKVGTI GLELVKSEEG EPVGDVEAAS LSKFSLNDTN VKVRMISDGA MEAELVVQSF
TIRDSRTQGT NKFRKIMSLI NNDVKQQFMA SVSISGGQDR NMIALLTIDS PRIILALDYL
FALQAFVNAG LATDEPLAIE EEAEQEDTDS DDEIMSPDGS RTLEAPKPTK EPAANGMNIS
FRVNLVDAQV VLIANPAMAS SEAIVLGTKQ VLISKQQAMT LQVDKVGMFL CRMDRFETNR
MRILDDFSIQ TALDIRNQGS KSSMMSITVD IEPLVLRLSL RDILLAMQIV NRASAMTAPA
EKSIPSAEAQ KLKPSAQSKK GTSQAAKTST HKPQAKSLAT TKRSTQQASQ QQRQNPSAVI
KREELHVSFE GIRVVLIGDV HEMPMLDWRV KKFGVDVRDW SGAMVADTSV DTLVNVYNFS
KSAWEPLIEP WSVGFHMSKD QNPGKLTVDL YSRKSMELTV TAATIALGSK SFDFLTSDDD
ILSKPRGGDA PYRVRNYTGF SLDIWAEGKE EEGFAAKLED GEEKPWRFED PMSARETLST
DGATGMLGIK LEGSGFDSLQ RVQVHREGEF LYNLKPKQDR IQHRLLIDVK LGSDNVKNIT
IRSPLLVENN TQIPIELGMF SPEDGHLLKI DKIPPGDARP APVGACHMHS IIIRPDQGFG
YAWSNERLFW KDLLKRPTRT ITCRGEQDEQ APPFFFQLHA AYDKKDPLTG VYPYMRLRLQ
APVEVHNLLP YDFKYRIYDS NTKKDWTNFL RKGGISPVHV VELSHLLLIS VEMQDGPFKP
SKFGIINSTD RESFRREKVL EIKDNNDTTL HLNMHFFNFP DGGGAFKVAI YSPYIVLNRT
GLQLDVRAQQ SMAQGRAAAG QGVVTDNQQD AGKALPFMFS YPTENKKNRA LIRVGDSNWS
KPQSFDAIGS TYTVALPSAK ARSDMHLGVS VSEGEGKYNL TKTVSIAPRF IVNNKMKEEL
LIREPGQSDW MTVKDGELFP LRWLRQGGAP QLSLCYPGVN NQWSSPFNIS NVGNVHVKLS
KAGQRQKLVR VDILMEAATI FCHVSVENKH WPFSFKNMSD QEFLYWQANP NLDEDEDDRG
SGFRPIRYRL PPRSIMPYAW DFPAAKNKEI VISANGRERH VKLAEIGPLI PFKIPPGQEG
GGMKVIDLNV VAAGPTQTLE VANYKPSKSM YKQKSTTSSS TATGFEVKDM DTDVTFKAQL
RLAGIGISLV NRHLKELVYV TLRDIEMKYS DSPLYQMVNM QVKWIQVDNQ LYGGIFPIIF
YPSVVPKTGK EMEAHPIFQS TITKVKDDSY GVLYIKYFTF LLQQMTVEID EDFIFAMIDF
ANIPGASWTE EKQGKLWDDN LSIPEPKQEQ SGQDVYFELL HLQPMQIDLS FVRTERINAE
DTMSTSNPFM FAVNVLTMSI GNVNDAPVRY NSLMLENARI STTALINNIK NHYVQESLRQ
VHVIIGSADF LGNPVGLFNN ISAGVADIFY EPYQGLVKSD RPEDLGIGIA KGASSFVKKS
VFGFSDSMAK FTGSMSKGLS AATLDKEFQD SRRMSRSRNR PKHALYGITS GGNAFASSLA
SGLGGLARHP LQGAEKEGAL GFVKGVGKGL LGVPTKAAIG AFDLASNMAE GVRNTTTVFD
QEGLDRVRLT RFIGTDGIVR PYSQREALGQ FWLKTLDNGK YFNEDYIAHL ELQNKEMLVM
LTYNGLMMVR TKKLQTEWDV PLKDVQTISK ERTGLGITLK GASRLALKSI AAPTAARPAA
NFTRTAPSLQ WATQFGSLAA RRPQLAQAAN ALKPSSSTIL RRSMADGKLT EAQKQAESRY
AREEIKPTPE TVTSSSSTHP LFSEVGAEAP ANEVDMMAGV KHDVNTVKDT FSLSQVPREA
LNLGLAGTLP YLATSLSTVY LSWELNHTTA GYGLMFSEKN ATYLLHILEP LQIGYGASIL
SFLGAIHWGL EWAGYGGYQG YKRYAIGVVA PMVAWSTLLM PIEGALIGQF LGFVGLYYVD
TRATYRGWTP SWYAVYRFVL TMIVGASIVA TLIGRSELPE HIPGSVDRAK VFHDEGSSEE
KLAEHETAAT EKKKNAARAD DRGGK
//
