ID A0A365MQT6_GIBIN Unreviewed; 1115 AA.
AC A0A365MQT6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=ADP-ribosylation factor GTPase-activating protein {ECO:0000256|RuleBase:RU369028};
GN ORFNames=FPRO05_05500 {ECO:0000313|EMBL:RBA10911.1};
OS Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA10911.1, ECO:0000313|Proteomes:UP000251714};
RN [1] {ECO:0000313|EMBL:RBA10911.1, ECO:0000313|Proteomes:UP000251714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA10911.1,
RC ECO:0000313|Proteomes:UP000251714};
RA Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA Sreenivasaprasada S.;
RT "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT strain ITEM 2341 from Date Palm.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: GTPase-activating protein for the ADP ribosylation factor
CC family. {ECO:0000256|RuleBase:RU369028}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU369028}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBA10911.1}.
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DR EMBL; PKMI01000061; RBA10911.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365MQT6; -.
DR Proteomes; UP000251714; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd07608; BAR_ArfGAP_fungi; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF160; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|RuleBase:RU369028};
KW Cytoplasm {ECO:0000256|RuleBase:RU369028};
KW GTPase activation {ECO:0000256|RuleBase:RU369028};
KW Metal-binding {ECO:0000256|RuleBase:RU369028};
KW Repeat {ECO:0000256|RuleBase:RU369028};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|RuleBase:RU369028};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 651..757
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 832..956
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 539..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 760..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1074..1115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..557
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1115 AA; 123252 MW; 9BD20A28F23DB83D CRC64;
MGIVSSKPEE GPALYLRDQN RLSISSLVVT NPRKRTSVNV VPNAFPATRI SAQRPLGDTS
PVEFVQDPDV SNPTSPPNFL VKLSNDDELI FSFTFVMRQA QHAQPATSSE PASGPIDTSI
SGLTYVYASN LKEVENLVTR EFHADPNLHR NANVALVGDY TTGGSPSVSF EWTWKWKPPK
PTEDKGGGWR NSCSFVEYDP RAHRLHTLAS FSYFVAGTNP RDALYPSSAH AFAGTPASLS
HPNSPSPPFL LASPPKIRVA SSQSVDSRIT APDIIDEPVS PLIPMAEMPL TPGFPQAKET
VKVDIACPKP NEESMVSDDG PVFRATLKAL EQKTGNMRTQ MKKVLKKAEH AHSCQSEAND
AFTAFVDALR EAAATNANAV QPALTHYFDK IAREILAYER QNTYHLQKII IEPVTKLYQV
DIKQAESKKR DFEEESKDYY AYVSRYLGQR QDSVKAKKLA EADSKYQNKR RNFELKRFDY
SSFMQDLHGG RKEQEVLSHL TRFADAQTRG FMDTAKKIEF LLPQLEALSN EVQEADKEYQ
YQRREREEKR RLLEVSNTPY KEPEQNSTTS NMPSGSATNG NAGNTSDSDL GRADSTGSQL
NAGSVNVPSG VELSRSPGSL GQTGVGSPAA ASKFKGIRDL EERDNMPSAV THRKEGLLWA
LNRPGGHVDP RNLNKQGWHK FWIVLDQGKL SEYSNWKQKL DLHIDPIDLR MASVREARNA
ERRFCFEVIT PSFKRVYQAT SEEDMNSWIT AINNALQSAM EGRSYQGKPT SSNGDSSLRR
DIGSVLTGKT QSLSHGSHHS TANPGIPSRR ITVGARPSAV RTSSSGYDEN PDRVLQMVRD
NDQGNLWCAD CGSGSKVEWV SINLGIILCI ECSGIHRSLG THISKVRSLT LDIKSFTIDI
VELLLLIGNR VSNMIWEAKL DQSLKPTAQA SREQRLRFIT SKYVDRLFVE PISPTLSRYG
TADETLLAAI KKNEIQQVLY ALALKANPNT VDKMRGTHAV WLALAAADPA APSPGTPHTA
TDAEAKAVPF PVAELLVQNG AEIPATMPAF PLGRFAQIYV EQKRGRTVIE GSMDAVPSLP
SNMSPAERLQ REKEARLQKR VSTGGRLARS PIPER
//
