ID A0A365MQV3_GIBIN Unreviewed; 1112 AA.
AC A0A365MQV3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=DNA mismatch repair protein {ECO:0000256|PIRNR:PIRNR037677};
GN ORFNames=FPRO05_05508 {ECO:0000313|EMBL:RBA10919.1};
OS Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA10919.1, ECO:0000313|Proteomes:UP000251714};
RN [1] {ECO:0000313|EMBL:RBA10919.1, ECO:0000313|Proteomes:UP000251714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA10919.1,
RC ECO:0000313|Proteomes:UP000251714};
RA Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA Sreenivasaprasada S.;
RT "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT strain ITEM 2341 from Date Palm.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family. MSH3
CC subfamily. {ECO:0000256|ARBA:ARBA00007094}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBA10919.1}.
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DR EMBL; PKMI01000061; RBA10919.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365MQV3; -.
DR Proteomes; UP000251714; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF122; DNA MISMATCH REPAIR PROTEIN MSH3; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR037677};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PIRNR:PIRNR037677};
KW DNA repair {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR037677};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR037677}; Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 962..978
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1112 AA; 122892 MW; 6DD72F73C483DADE CRC64;
MAPTPKSSEK KQRSLTSFFT PKTVNGLAAV FEKQSRAQAA KSQSQSQSQS EPQSSSRDNE
SQSRKRAPDD ALKENEKPGK APKRARVDDT PANEDTSTFF SRSKAGDQET TGTRTERYRY
DGSSAPTTQD GNKNTEPMQH EDEDAEERRQ HQELHKRFVK KLGHPDALAW RRNLQDAALA
GEDEDADADE EDAPAPAKTK KKGSKTGKLT PMEIQFLDIK RKHMDTILIM EVGYKFRFLG
EDARIAAKEL SIVCIPGKMR YDEHPSEAHL DRFASASIPV HRLPVHAKRL VAAGHKVGVV
RQIETAALKK AGDNRNTPFV RKLTNLYTKG TYVDENGELD QSGGSGAPSG GYLLCITESK
AKGWGTDEKV DVGIIAVQPA TGDIIYDNFE DGFMRSEIET RLLHISPCEF LIVGELTKGT
DKLVQHLSGT STNVFGDRSR VERVPKSKTM AAEAYSHVTQ FYADKLKENA QDETAAALLE
KVLKLPESVT ICLSAMINHL QEYGLEHIFD LTKYFQSFST RSHMLINGTT LESLEVYRNS
TDHSEKGSLF WALDKTLTRP GHRLLRKWVG RPLLDQQLLE ARLNAVEELL EKQSTIPVSQ
LESLLANTKT DLERSLIRIY YGKCTRPELL SVLQALQRVA TYYSTVKSPS DAPFSSSLLG
DSVCALPQIL DTVASYLERI NLVAARNDDK YGFFRDEFQT EDMQDHQLGI AHVEHELDGH
RAVAAEKIRK KTVDYVTVAG IEYLIEVPNT DIKNVPASWA KISGTKKLSR FHTPEVLRLI
TERDQHREAL AAACDKAFTD LLASISADYQ PLRDAVSALA TLDCILSLSK VAAQPGYSRP
SFLPSTADPT ISITNGRHAI AEHTLDGSYI PFSTSLMHPS PLAHLITGPN MGGKSSFVRA
LALIVLLSQV GSYVPADALS LTLCDAIHTR TGARDNLFAG ESTFMVEVSE TARILRTAGP
RSLVILDELG RGTSTHDGAA IAQAVLQHVV TETRCLTLFI THYQNLARVA EGLDGVKNVH
MKFKAEKGED GEEQVTFLYE VGEGVAHRSY GLNVARLARI PKKVIDVAAL KSGQMEQEMK
IRRFRGVCRA LSDVIHGGPD HLDQLVSGIE QL
//
