ID   A0A365MRW9_GIBIN        Unreviewed;       333 AA.
AC   A0A365MRW9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE            EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
GN   ORFNames=BFJ72_g12793 {ECO:0000313|EMBL:RKL27885.1}, FPRO05_04462
GN   {ECO:0000313|EMBL:RBA11289.1};
OS   Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA11289.1, ECO:0000313|Proteomes:UP000251714};
RN   [1] {ECO:0000313|EMBL:RBA11289.1, ECO:0000313|Proteomes:UP000251714}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA11289.1,
RC   ECO:0000313|Proteomes:UP000251714};
RA   Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA   Sreenivasaprasada S.;
RT   "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT   strain ITEM 2341 from Date Palm.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:RKL27885.1, ECO:0000313|Proteomes:UP000283569}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fp_A8 {ECO:0000313|EMBL:RKL27885.1,
RC   ECO:0000313|Proteomes:UP000283569};
RX   PubMed=30202022; DOI=10.1038/s41598-018-30335-7;
RA   Armitage A.D., Taylor A., Sobczyk M.K., Baxter L., Greenfield B.P.,
RA   Bates H.J., Wilson F., Jackson A.C., Ott S., Harrison R.J., Clarkson J.P.;
RT   "Characterisation of pathogen-specific regions and novel effector
RT   candidates in Fusarium oxysporum f. sp. cepae.";
RL   Sci. Rep. 8:13530-13530(2018).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00000966};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBA11289.1}.
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DR   EMBL; PKMI01000050; RBA11289.1; -; Genomic_DNA.
DR   EMBL; MRDB01000069; RKL27885.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A365MRW9; -.
DR   VEuPathDB; FungiDB:FPRN_00259; -.
DR   Proteomes; UP000251714; Unassembled WGS sequence.
DR   Proteomes; UP000283569; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR34142:SF1; CELLULASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR34142; ENDO-BETA-1,4-GLUCANASE A; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW   Hydrolase {ECO:0000256|RuleBase:RU361153};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..333
FT                   /note="cellulase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033354775"
FT   DOMAIN          39..301
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
SQ   SEQUENCE   333 AA;  36334 MW;  EC996BDF5555625F CRC64;
     MRFTDFLLAS AGASLALAAP HTTRAKGKFL FTGSNESGGE FGEGNLPGTL NKDYIWPTTS
     SIDTLASTGM NTFRVGFRME RVTPSGITGA IDEAYFKGLQ DTVNHITSKG HYAVIDPHNY
     GRFNGNIIKS SDFSVWWQKV AKRFANNKLV IFDTNNEYHD MDNSVVAALN QAAVDAIRKA
     GATSQYIFVE GNAYTGAWSW VSSGNGAAMK DLKDPQNKII YEMHQYLDSD SSGTSENCVS
     STIGAERLKA ATQWLKANKK KGILGETAGG ANAQCIAALK GELQHLLDNS DVWTGWLYWA
     AGPWWGDYMF SMEPTTGTAY KKVLPQIKQF IGA
//