ID A0A365MX41_GIBIN Unreviewed; 1209 AA.
AC A0A365MX41;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Cell division control protein 25 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BFJ72_g12646 {ECO:0000313|EMBL:RKL28062.1}, FPRO05_13757
GN {ECO:0000313|EMBL:RBA13114.1};
OS Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA13114.1, ECO:0000313|Proteomes:UP000251714};
RN [1] {ECO:0000313|EMBL:RBA13114.1, ECO:0000313|Proteomes:UP000251714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA13114.1,
RC ECO:0000313|Proteomes:UP000251714};
RA Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA Sreenivasaprasada S.;
RT "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT strain ITEM 2341 from Date Palm.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RKL28062.1, ECO:0000313|Proteomes:UP000283569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fp_A8 {ECO:0000313|EMBL:RKL28062.1,
RC ECO:0000313|Proteomes:UP000283569};
RX PubMed=30202022; DOI=10.1038/s41598-018-30335-7;
RA Armitage A.D., Taylor A., Sobczyk M.K., Baxter L., Greenfield B.P.,
RA Bates H.J., Wilson F., Jackson A.C., Ott S., Harrison R.J., Clarkson J.P.;
RT "Characterisation of pathogen-specific regions and novel effector
RT candidates in Fusarium oxysporum f. sp. cepae.";
RL Sci. Rep. 8:13530-13530(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBA13114.1}.
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DR EMBL; PKMI01000031; RBA13114.1; -; Genomic_DNA.
DR EMBL; MRDB01000067; RKL28062.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365MX41; -.
DR Proteomes; UP000251714; Unassembled WGS sequence.
DR Proteomes; UP000283569; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR CDD; cd11883; SH3_Sdc25; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 67..126
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 786..919
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 955..1192
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..166
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1209 AA; 135204 MW; E0C5AA6B9B37D9F1 CRC64;
MLKIQTAAVP PSIHSSRTIH DPSGDSPSAS VRITTAASVQ ASDQQASTTR ADPAWGLMNG
IVGTAPMGAM YVRALYDYEA DDRTSLSFHE GDVIQVITQL ESGWWDGVIN GVRGWFPSNY
CQLITSPDDI PDSAHNGTFD AVEDDAEDPE MYDDQYDQDD DSEQDGPIAL PLEGTDGGDN
SRADFWIPQA TPDGRLFYYN MMTGDRSMEL PLESPVSSNE TGPRDRMNVN IPDKTRPPPE
MMARGLTQDE DDEYLTSASE AEGDSSRLAS RRSKHTKRAS FGALSPSTSM DSINGASPVG
RLRNGASSNG HLTAGQVPNI ASATSFTSTT YNLPTTATVP RSFFDDGSTP SLSWTLLVSN
MRRAIDRYRE AIMNNNRSEY VAKAEDISDH LRLLLAAGSG TTDNHSGQPS IISTNKALYP
HFRDMMSKFS KLVISSHIAA ADWPNAESIQ KCLQEADGVL MGVYSYVEVA RQQRGEEIPR
LFPGFVIGSN TGGSWQNNGL GPRDEITANF LEDEEGVVEP TAILDNKMLE RLDEQKRILV
SSIRELDKSL VVLEKIVTPY RHEVIGNNVC FAGGRVLDTF RQWIAMIESI DLSSLGNSFQ
TPQLADLGTH KQSLYDNISD LILGCQAVAG PLADEWSEVR GEALENRLEY VRQCARALET
NSSHIGFSLQ LLSEQVQINM QQHQAEVRPR GNSFVRSTLQ RGETMPYDRP HQRTESRTAP
VRPPLITSQS FTEGEPAPGN MRRGDYSKVK KIFGEDPSPQ VPVTEDTPEF LLLDYEHEVS
WDSKTSPPTV KGGSLLALVE QLTRHDKLDS NFNNTFLLTY RSFTTARELF EMLIKRFNIQ
PPEGLSQADF EIWRDRKQKL IRFRVVNILK NWFDNFWMED YNDESKQLVR DVYSFAKDTV
KSTETPGSAP LMAVLDQRLS GKEAGARRMI QTVNQNTPTP IMPKNMKKLK FLDIDVVEFA
RQLTIVESRL YGKVKATECL NKTWQKKVPE GEPDLAPNVK ALILHSNQMT NWVAEMILAQ
MEVKKRVVVI KHFVSVADRC RSLNNFSTLT SIISALGTAP IARLKRTWDQ VPQRTHATLE
SMRRVMASTK NFGEYREALH AANPPCIPFF GVYLTDLTFI EDGIPSIIKK TNLINFAKRA
KTAEVIRDIQ QYQNVGYSLQ PVPELQDYIL NNMQAAGDVH EMYDKSLQVE PREREDEKIV
RVLAESGFL
//
