ID A0A365N189_GIBIN Unreviewed; 338 AA.
AC A0A365N189;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 8.
DE SubName: Full=Dihydroflavonol-4-reductase {ECO:0000313|EMBL:RBA14540.1};
GN ORFNames=FPRO05_13351 {ECO:0000313|EMBL:RBA14540.1};
OS Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA14540.1, ECO:0000313|Proteomes:UP000251714};
RN [1] {ECO:0000313|EMBL:RBA14540.1, ECO:0000313|Proteomes:UP000251714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA14540.1,
RC ECO:0000313|Proteomes:UP000251714};
RA Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA Sreenivasaprasada S.;
RT "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT strain ITEM 2341 from Date Palm.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBA14540.1}.
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DR EMBL; PKMI01000027; RBA14540.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365N189; -.
DR Proteomes; UP000251714; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR CDD; cd05227; AR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF579; 3-BETA HYDROXYSTEROID DEHYDROGENASE_ISOMERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G02250); 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 12..232
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 338 AA; 37183 MW; 99E58BD561641351 CRC64;
MVSSPPAIQY VLVTGATGFI GAHVVDQLLS RGMKVRGATR SLLKGKAMID ARPEFREKLD
FVQVDDFENP GGFEEAIQDV DAVIHVASPF TYDTKDNEKE LVTPAINGVD SILKAAATSL
KVKRVVITSS FASVLDDRRK APPYFTYTGD DWNSLSYEES VDPETSAVIA YRGSKKFAEL
KAWDIMAKEK PSFDLVTLCP PMTFGPIRHP VTSVDALNES NKMLFKIACG ESPLPVARVP
FWIDVRDLAK AHVEALLRPE AGGKRYIPAS PERFTYSKAA NIIGSHFSWA ADNVSKEVQA
PDESHGVDGE TAGRELGLDY KPFTRTVIDL ITQVKDMR
//
