ID A0A365N417_GIBIN Unreviewed; 876 AA.
AC A0A365N417;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=FPRO05_12529 {ECO:0000313|EMBL:RBA15455.1};
OS Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA15455.1, ECO:0000313|Proteomes:UP000251714};
RN [1] {ECO:0000313|EMBL:RBA15455.1, ECO:0000313|Proteomes:UP000251714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA15455.1,
RC ECO:0000313|Proteomes:UP000251714};
RA Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA Sreenivasaprasada S.;
RT "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT strain ITEM 2341 from Date Palm.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the engrailed homeobox family.
CC {ECO:0000256|ARBA:ARBA00010896}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBA15455.1}.
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DR EMBL; PKMI01000022; RBA15455.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365N417; -.
DR Proteomes; UP000251714; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR24341; HOMEOBOX PROTEIN ENGRAILED; 1.
DR PANTHER; PTHR24341:SF6; HOMEOBOX PROTEIN INVECTED-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 374..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 584..644
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 586..645
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 463..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 319..357
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 485..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..537
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 876 AA; 97919 MW; E8E79E269B3B640F CRC64;
MDKAQFSPSL TGSRSVRVWT NMSNPELPNR FGEEMGTHGI SPLSTPGYID RLYDLAAQAN
RPVILNIALG THEYDRGFEI QLLGCFPNFP IHLLADIYES STWGRGTVIL PNTTDERSVA
FLANYPQVQA ASHSQGGPKD DITPAQVKFL PILGWCSSVE RPITGSQQDT QRIAIVVTIS
FHECVPEKMG EFWSIGRRQD RLAKFEQWAF LDLAATFSGW PTIWTNARRE LAQRHASMYS
SANAVADLGT TRIIHQDMAN VIALREDLRL FIAAYAKYSQ ILRRMFPNSK MARINKMRSL
TGRRRKEGQP MDNVELKEST ELLELLAELE IRLQDSQQNL EHQLETSEVI LRQLENLLSL
AFNTQAIAQG QATAMLNVLA TIFLPLSFVA SVFGMTKFQI SAVWYPPAAA IVLFLVGGAI
LLLRWLGVDM NMIRLPMKPV SAFISKQQKP TFRLLNTGPE AANPGICAET KEQRGLDPKG
TQRQELVKSA RSSLDDTSSL SPGARKQPAT LRKLENSQAG ENREENYIYD DGEPGKPDGN
AHYTLLLQPE PHSGTQIKAH MEDSRDSATS KPDMMDDSTS TTLSHHPVSK PRLTKSETEF
LEAEFQKTPK PNHQRKSEIA DLLQVDKPRI NNWFQNRRVK EKQIQRTRML EAQPVVEWRN
ERILHGGQML HSSEPSDSPP VGSISAGETG KVVQHLGGTP QDYRVTGGGV PHFTANTELQ
LQRLQGLQVQ MPTISPPRNG ILMPARDPKH VLRDIQMQVM LLEQQNEKRP KPQTGQRVDD
PPSCLPARDS KHVLRDYQMQ LMFLEQRNKK RLMMARSEQD AAGGEGSRDA AGKSNFSSVE
GRPKPQAEHR VNGSLSCQQD NELAGAGIVP AVVRDV
//
