ID A0A365N933_GIBIN Unreviewed; 2522 AA.
AC A0A365N933;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:RBA17285.1};
GN ORFNames=FPRO05_02009 {ECO:0000313|EMBL:RBA17285.1};
OS Gibberella intermedia (Bulb rot disease fungus) (Fusarium proliferatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=948311 {ECO:0000313|EMBL:RBA17285.1, ECO:0000313|Proteomes:UP000251714};
RN [1] {ECO:0000313|EMBL:RBA17285.1, ECO:0000313|Proteomes:UP000251714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ITEM 2341 {ECO:0000313|EMBL:RBA17285.1,
RC ECO:0000313|Proteomes:UP000251714};
RA Almiman B.F., Shittu T.A., Muthumeenakshi S., Baroncelli R.,
RA Sreenivasaprasada S.;
RT "Genome sequence of the mycotoxigenic crop pathogen Fusarium proliferatum,
RT strain ITEM 2341 from Date Palm.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBA17285.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PKMI01000017; RBA17285.1; -; Genomic_DNA.
DR Proteomes; UP000251714; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05195; enoyl_red; 1.
DR CDD; cd05274; KR_FAS_SDR_x; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF28; SYNTHASE, PUTATIVE-RELATED; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF13489; Methyltransf_23; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 87..506
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2439..2516
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1385..1412
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2522 AA; 274232 MW; 8757454154A8BD5B CRC64;
MTQMNSHSEL NGHNGELSNG TMNVHVNGHV NGHTNGQTNG HTNGHALNRN QTEGISGGIT
NGHSTQSNGH AMPIPTASEA DAPKSSFEPI AICGMACRLP GGIASPSDLW EFLLEGGDAR
SRVPMTRFNI DGYYNAHKAG SANCQYGYFL DESVDLAGLD TSFFSMSRRD VEWLDPQQRL
MLEVARESVD DAGEVNFQGS STGVYIGSFA NDWYDIMGRD PLHRSVVSTI ASHDFMISER
ISHEMDLRGP SMTIRTACSS ALVSLNEACM AIGKGDCESA IVGGTSLILA PDLLTRLADQ
GIISPDGSCK TFSAEANGYA RGEAIVSIYI KSLSAAIRDG NPIRSIISGA AANFDGKTNP
LTNPSVTAQE TLIRRAYSVA GIPDVSKTAV FECHGTGTAT GDPIETEAIA AVFGEQGIYL
GSVKPNLGHS EGASGLTAVL KATLSLEHKM IAPNIKYSPV NPKIPFERAK LVIPEEPTSW
PAGRDERISI NSFGVGGSNA HVIVESIESF MASHPQVIAK PVTEPDSQDE GPRLLLFSAK
TTPSLKAMTA SYQALFDSGD VSNLSDIAYT LANRREHFTH RSFAIATREN IEVSTSVLSR
DNPYSPSSLI MVFSGQGAAW PQLGRELLLS NSVFSGTINA LQEHLGTLGP ASPTWSLAEE
ILKPARTSRI YEAEFSQPLC TALQIALIDT FASVGVKPDA VVGHSSGEIA AAYAAGALTA
REAIIIAFFR GSTTTEQKNL QGGMAAVGLG WAEAEKHLKP GVVIACDNSP TNVTISGDIE
PLQAVVAEVK EAHPGIPATT LKVDKAYHSH HMLGAGEIYH AALVDSGVVG KAPQIPFFSS
VTGELLSGTE KANQLGPKYW QTNLERPVLF RSAVSSTIAS SEPNHHQVFL ELGPHSALAG
PLRQILTDKA SKASYVPSLV RKQDSVENFL QAIGKLYTLH MDVDLKSLFP TGSCVASLPC
YPWNHQNRLF FESRLAKEWR EREFPDHNLL GIRSHESTSL EPSWRNLIQV SRTPWIADHK
IGETIVFPFA GYIAIASEAC RQITGIQEGV SLRNVKVHTA LVIEEDGATE IVTTLRRVKL
TEEQDSEWWE FSVSSHNGHV WIKHCWGQVR GEQSPFPEKE AIKKSDDVLP REVNASKWYE
VVSEEGLTYG PAFNTMESIC TSTKPPHQAS TTIQNGEDRW DDASEYHMHP IVLDTFYQLV
SCTSTLGICR DYRRLVASSI EFMTMARCND ERVSIEVSSE LGQDLVGSGT VFSGSRPVMR
IINSHSSFFE EGDVGENAKV PITARCEWVP DIDLKSLGDL VTCPEDTADS FSNLTELSKI
LVTQAHRLAA SVDVQVPHLT KYKNWLDKVM DPNLAAYDDA DLANMSKSLS QKIHDNGTSP
ARLAAEAMTA TYNKLSDLLS QQEAEVTELD SLSPLELVSQ PDISDFLLCL GNKKPTLRVL
DFYSGSIETT SKAIEVLTRN DGTHLFSKYT IATPLLGMPE ASNEHLKKLV PDIEFTTLDL
SQSLADQGFD DRQFDLIIGS GAISSARNVE KSLETLRNLL SPAGRLLLEE PRPDSLWVKF
ILGTTQRWWS HEDGRIEGPI VDLETLQRLL ETSNFANVEQ LSLAPWAATV VVARREPQNT
PTKRITLLCH GGGPSELTRE LEAQGYDVDR CFLDQTPPLG QDIVAVLDEQ GPFIESIDAD
GFTKLKTFLN SVQNPNGLLW VTRQSSVGCQ DPRFAQIIGF TRTLRNETST DIAVCEVDNI
TSPENLATLV KVLAQFQTRS QDGVLGPDLE YVISKGEVLV NRIFPAAVGK ELEDKVSESE
AYITMTQPGR MESLFWASQP PTDPKDNEIE VEVYASGLNF RYVLVAMGII PPPKSLKFGY
EAAGVVRRVG SNVTKLRPGD RTVFVGEDTF STVVRVPELL AQKLPDDISF VEASAIPIVF
LTAVYGLIDL GRLTRGQSVL IHSGCGGVGL AAIQVARMLG ADIYTTVGSE AKVEYLTKTF
DIPRSHIFSS RDASFATDLL RETGGKGVDV ALNSLSGELL HTTWKCIAKW GTMVEISKRD
LLQNAQLDMS PFLQNRNYCC LDVDQLRAER PEVINRLLSF IMNCFSNRIL KPIRVDQVFP
GSAVLDAFRH MRQGKHMGKI VLEIRDATGK PLTGPVQATK TTNLQLDGSA SYLLVGGLGG
LGRALSVWMV ERGARNLVFL SRSAGGSTQH DKFKQEIESM GCSVQFIRGD VTSAGDVTRA
IGEVSSPLKG IIQMSMVLRD RMFEDMTFQE WEATTRPKVQ GTWNLHKASL AAKCPLDFFL
LFSSLSGILG QVGQANYASA NTFLDSFARY RAGMGLPCTS LDLGAMEGIG YLNENQELLR
KMKGTGWRTV GESELVEALN VALMPPSSPQ EYGDAFLLGV APTVPLGSAE SSTRLSKDVR
MAAYHNIGRG QSGALPANDG LRAFLSSVKK DPSILKSHES VNTLALEIGK KLASLLLTGD
VDLDISMNTA DMGLDSLVAI ELRGWWKLTF GFEISTLEML SMGTLEALGK RTADGLKGLY
DS
//
