ID   A0A365T3B4_9EURY        Unreviewed;       880 AA.
AC   A0A365T3B4;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=GAF domain-containing protein {ECO:0000259|SMART:SM00065};
GN   ORFNames=DMJ13_26845 {ECO:0000313|EMBL:RBI58441.1};
OS   halophilic archaeon.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales.
OX   NCBI_TaxID=29295 {ECO:0000313|EMBL:RBI58441.1, ECO:0000313|Proteomes:UP000252983};
RN   [1] {ECO:0000313|EMBL:RBI58441.1, ECO:0000313|Proteomes:UP000252983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H22 {ECO:0000313|EMBL:RBI58441.1,
RC   ECO:0000313|Proteomes:UP000252983};
RA   Chen S.;
RT   "Draft genome sequence of Haloarchaeon sp. H22 isolated from a salt mine.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBI58441.1}.
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DR   EMBL; QNGA01000016; RBI58441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A365T3B4; -.
DR   Proteomes; UP000252983; Unassembled WGS sequence.
DR   Gene3D; 3.30.450.40; -; 2.
DR   InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR007050; HTH_bacterioopsin.
DR   InterPro; IPR025847; MEDS_domain.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR   Pfam; PF15915; BAT; 1.
DR   Pfam; PF13185; GAF_2; 2.
DR   Pfam; PF04967; HTH_10; 1.
DR   Pfam; PF14417; MEDS; 1.
DR   SMART; SM00065; GAF; 2.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000252983};
KW   Transcription {ECO:0000256|ARBA:ARBA00023015};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          340..478
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
FT   DOMAIN          506..660
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
FT   REGION          74..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   880 AA;  98113 MW;  1F636D53B2D9B405 CRC64;
     MLDDGPYAMI VRPNRPDHAS GLNEQLVDDS ERLEVSETAV RCGREAVFRV DRPACATLLW
     LPCLPLYTMT NDPGPNGPSS NTPHSVRSRH VPGSAAADRF EFDSNVEETD PHHHIAILYE
     TPQQQFAAVV PYIRDGLERG DRCLYIYDDN DREAVEAAMR EAGIDVDAAV ASGDLSFHSK
     DDSFLQDGDF EPDDTIDFAT ETIREATEED GYDAVRITGE MTFVLDGDHD VEQMIEYEHA
     LNDVFGTRPV LGICQYNVTH FDPEILNQII RAHPNLVYDG TVRRNFYYLP SEEITGGEHS
     PTDQSVQSLL DRVTAYEQLQ RREQGLSALS DATQELMQLD AGNITGRIGD IVREVLDVTF
     ASVWVYDETT GELELQSGST RDYQTATTLA DRYEERAWQA FVTGQTEVLD KLSPDISADP
     SQHQLQSGIV VPFGRHGVFC AGSIHPNVFD DPTVEMANTV GANIETALDR ADRERTVEER
     NEKLERLNRI NQVIREIGEA LVEADTRDDI QEMVCERLAA ADPYRFVWIG ERDVETDTVT
     PRASAGGHDG YLDGVTITTD ENGPTERGPI STALQTQTVQ HVQDVLIDPA VKPWREATLA
     HGFRSCISVP LVYEQTSYGV LTLYSGEPNA IDEMERDVLA ELGETIAHSI DAAETRETLQ
     TDTVTELTLS VQELDDVLGC LAREVGCEIE FDGLVQSDGP VHHFFTTRDT DPDAVVASGS
     QIDGITDTEL ISRDETHCTF EATVTEPTLA SRVVDQQAVL QSFTITDETS TLVVDLPPTT
     EVREFVEMVR SVYPGTDLVT RHTRNRSIAS QQDLRDTLDD RLTDRQREIL EMAYLSDFFE
     SPRTRTGNEL STALDISQPT FAHHLREAQR KLCELVFENA
//