ID   A0A365TE54_9EURY        Unreviewed;       376 AA.
AC   A0A365TE54;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN   Name=cdc6 {ECO:0000313|EMBL:RBI63441.1};
GN   ORFNames=DMJ13_02575 {ECO:0000313|EMBL:RBI63441.1};
OS   halophilic archaeon.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales.
OX   NCBI_TaxID=29295 {ECO:0000313|EMBL:RBI63441.1, ECO:0000313|Proteomes:UP000252983};
RN   [1] {ECO:0000313|EMBL:RBI63441.1, ECO:0000313|Proteomes:UP000252983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H22 {ECO:0000313|EMBL:RBI63441.1,
RC   ECO:0000313|Proteomes:UP000252983};
RA   Chen S.;
RT   "Draft genome sequence of Haloarchaeon sp. H22 isolated from a salt mine.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000256|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC       Rule:MF_01407}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBI63441.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QNGA01000001; RBI63441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A365TE54; -.
DR   Proteomes; UP000252983; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR   PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR   PANTHER; PTHR10763:SF32; ORC1-TYPE DNA REPLICATION PROTEIN 2; 1.
DR   Pfam; PF13401; AAA_22; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW   Rule:MF_01407}; Cell cycle {ECO:0000313|EMBL:RBI63441.1};
KW   Cell division {ECO:0000313|EMBL:RBI63441.1};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705, ECO:0000256|HAMAP-
KW   Rule:MF_01407};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW   Rule:MF_01407}; Reference proteome {ECO:0000313|Proteomes:UP000252983}.
FT   DOMAIN          54..375
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          302..374
FT                   /note="Cdc6 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01074"
FT   BINDING         66..70
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         209
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT   BINDING         221
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   376 AA;  42494 MW;  07CE6C9B9B78EE37 CRC64;
     MADDPEEGML SWDETVFRDE HVFEIDYVPE TFEHRESQMQ SLQYALRPAV RGSRPLNVMA
     HGPPGTGKTT AVQKLFDELS AQTDVRTVRV NCQVDSTRYS VFSRIFEGIF EYEPPSSGIS
     FKKLFRQITD KLVEDDEVLV VALDDVNYLF YENEASDTLY SLLRAHEAHS GAKIGVIVVS
     SDLNLDVIEE LDGRVQSVFR PEDVYFPVYD PSEIVDILDE RVERGFHDGV ISTEVLDEVA
     ELTAESGDLR VGIDLLRRAG LNAEMRASRT VSVEDVEEAY EKSKFVHLSH SLHALSDNEE
     ALVRVIAEHD GEQAGDVYDA FHDQTELGYT RYSEIINKLD QLGVIDATYT NVDGRGRSRT
     LSLRYDPEAV LSRLEE
//