ID A0A365YRI8_9ACTN Unreviewed; 384 AA.
AC A0A365YRI8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN Name=fxlM {ECO:0000313|EMBL:RBM04558.1};
GN ORFNames=DEH69_30645 {ECO:0000313|EMBL:RBM04558.1};
OS Streptomyces sp. PT12.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1510197 {ECO:0000313|EMBL:RBM04558.1, ECO:0000313|Proteomes:UP000252839};
RN [1] {ECO:0000313|EMBL:RBM04558.1, ECO:0000313|Proteomes:UP000252839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PT12 {ECO:0000313|EMBL:RBM04558.1,
RC ECO:0000313|Proteomes:UP000252839};
RA Devaraj K., Tan G.Y.A.;
RT "Diversity of actinobacteria isolated from Cape Rachado, Malaysia.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBM04558.1}.
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DR EMBL; QEST01000287; RBM04558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365YRI8; -.
DR OrthoDB; 4035289at2; -.
DR Proteomes; UP000252839; Unassembled WGS sequence.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027573; Methyltran_FxLD.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04364; methyltran_FxLD; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:RBM04558.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000252839};
KW Transferase {ECO:0000313|EMBL:RBM04558.1}.
SQ SEQUENCE 384 AA; 41144 MW; 557B26591BEE970E CRC64;
MVKELRSLEA ITSEPVAAAF TAVPRHTFAL DEPLEKAYDA DRALVVKRGQ DGAALSSLSA
AHIQAVMLEQ AGIEPGMRVL EVGSGGFNAA LLAELVGDDG TVVSVDIDAE IVERARTCLD
AAGYGQVKVV LADADNGVVA HAPYDRIVVT AGAWDVPSAW REQLSECGRI VVPLRMRGLT
RSIAFDRDGE GLVSGSYRLC GFVPMQGAGA YTERLVRVDE GIALRVDDQQ QDFDVEAVAA
AVRTPRLELW TGAAFDLPDE LELFLAASTP EMVMLHGRQD VVDQGFLAPS VTRGVPALVD
GGSFAYRTKR QNAATGGFES GVFAHGPDAQ AVAERYADLL RRWASDHRRR GAAHLRYRPM
PAGMAEPAPG VIAKRLGAVE ISWR
//
