ID A0A365ZIJ5_9ACTN Unreviewed; 749 AA.
AC A0A365ZIJ5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=RND transporter {ECO:0000313|EMBL:RBM18752.1};
GN ORFNames=DEH69_12295 {ECO:0000313|EMBL:RBM18752.1};
OS Streptomyces sp. PT12.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1510197 {ECO:0000313|EMBL:RBM18752.1, ECO:0000313|Proteomes:UP000252839};
RN [1] {ECO:0000313|EMBL:RBM18752.1, ECO:0000313|Proteomes:UP000252839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PT12 {ECO:0000313|EMBL:RBM18752.1,
RC ECO:0000313|Proteomes:UP000252839};
RA Devaraj K., Tan G.Y.A.;
RT "Diversity of actinobacteria isolated from Cape Rachado, Malaysia.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBM18752.1}.
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DR EMBL; QEST01000102; RBM18752.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A365ZIJ5; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000252839; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000252839};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 186..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 563..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 209..340
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 723..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 749 AA; 78150 MW; BD061ED59E914D1F CRC64;
MARRNDAGRG PLIRLGRLVA RRGGAILLAA AATLLGLGAY GAGAQADLDL ARWDAPGTES
VRAQEVLREE FGTGNPNLAL LVTAEGGDVD DPAVAAAGRD LADELAGHPM VSDVSSYWDG
GDPALRSSGG ERALILARLE GSATETRAEL ADLSPELARD SPRISVTVGG QEEVSRQIGE
QAARDFLTAE AIVLPSVVLL LILVYRRTVA ALLTVGVGLF SVLGTMAGLR LLAQFTEVST
FAANLALVLG LGLGIDYSLF LINRYREERA AGRAVDEAVA HAVPAAGRTI VFSGVTVAVS
LSTLLVFPFF FLSSFAYAGI LVVATAVAGA VVVLPAALVR WGHRVDRPAT GAPGRFWHRM
ALGVMRRPVL TGTAALAVLL FLASPLLGLR LGLPDQRTLP EGTSSRVASE EIRENFAAEP
TDTVFVVTEG ASDPAATAER AAALSRVEGV FHVISPEGIH RDGRRVGPAP ASAGKMTADG
TTRLSVVPTQ DAMDGDVPGL VADIRAVPAP EGTLVGGYPA ETTDFRATLL DRVPLVAALI
LLITCGVLFL MTGSVLLPVK ATVLNLLSLS VMFGALVWVF QDGNLSGVLG FTPTGSIEPS
IPMLMFCVTY GLSMDYEVFL LARVKEEYDR TGDTRAAVAA AIGRTAPLIT AAAGILVLTF
ATYATSGVVF LKELGIGTAL VILADATLIR MVLLPVSMRL AGRGNWWAPR PLRRLHARIG
LAESPAPAPE GPGGPGERGD AVLPREYAG
//
