ID A0A366DT34_9NOCA Unreviewed; 421 AA.
AC A0A366DT34;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:RBO92424.1};
GN ORFNames=DFR74_10367 {ECO:0000313|EMBL:RBO92424.1};
OS Nocardia puris.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=208602 {ECO:0000313|EMBL:RBO92424.1, ECO:0000313|Proteomes:UP000252586};
RN [1] {ECO:0000313|EMBL:RBO92424.1, ECO:0000313|Proteomes:UP000252586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44599 {ECO:0000313|EMBL:RBO92424.1,
RC ECO:0000313|Proteomes:UP000252586};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBO92424.1}.
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DR EMBL; QNRE01000003; RBO92424.1; -; Genomic_DNA.
DR RefSeq; WP_067510044.1; NZ_QNRE01000003.1.
DR AlphaFoldDB; A0A366DT34; -.
DR STRING; 1210090.GCA_001613185_03555; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000252586; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000252586}.
FT DOMAIN 281..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 281..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 383..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 44339 MW; 0F4B5AABB67F16BA CRC64;
MTTIDAGASL AGFTVGVTAA RRAEEFATLL TRRGASIVSA PAIRIIPLAD DTELERVTRT
LVAQPPQITV ATTGIGFRGW MEAAEGWGLA EDLRATLGAT RMLARGPKAK GAIRAAELRE
EWSPASESSA EVLDHLLAEG VEGVRIAVQL HGATTEWEPV PDFCEVLRCA GADVVPVPVY
RWIPPEDQGP MDQLIELIVT AGLDCVTFTS APAVASMLMR AKETGLLEGV LHALRGRVLA
ACVGPITAAP LEELGVPTSM PGRARLGALA RHVAEELPRR ASRIHAAGHI ISVRGACVVV
DGEVRQLAPA PMALMRSLAR QPGRVVSRED LLAALPGGGD DTHAVETAIA RLRAGLGTPK
AIQTVVKRGY RLALDAADCD PVPRDLTSPH AQPPAHTRPA APGIGNPVRS PRYAPQPMGS
W
//
