ID A0A366DU84_9NOCA Unreviewed; 819 AA.
AC A0A366DU84;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Chaperone protein ClpB {ECO:0000256|ARBA:ARBA00017574};
GN ORFNames=DFR74_10268 {ECO:0000313|EMBL:RBO93652.1};
OS Nocardia puris.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=208602 {ECO:0000313|EMBL:RBO93652.1, ECO:0000313|Proteomes:UP000252586};
RN [1] {ECO:0000313|EMBL:RBO93652.1, ECO:0000313|Proteomes:UP000252586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44599 {ECO:0000313|EMBL:RBO93652.1,
RC ECO:0000313|Proteomes:UP000252586};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBO93652.1}.
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DR EMBL; QNRE01000002; RBO93652.1; -; Genomic_DNA.
DR RefSeq; WP_067512162.1; NZ_QNRE01000002.1.
DR AlphaFoldDB; A0A366DU84; -.
DR STRING; 1210090.GCA_001613185_05197; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000252586; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:RBO93652.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:RBO93652.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000252586};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 35..179
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT COILED 430..476
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 819 AA; 89848 MW; EE806C24D2464F3A CRC64;
MTEGWPHSMN SFDDIFQRFF GPGMAARPPV QRIDLGRLMT DNAKLLVNSA REAARDWGNT
EVTPEHLLYA ATEAEPGRSI LAELGHDPDK VAEQMRTAED TGEPSEPADE TLILSPAAKS
ALRAAQRSAA EAGSSYIGPE HILLGIAELG DGPAARTLLT GAKNIAPGKQ EPSQTPTLDE
YGRDLTAEAR AGKVDPVVGR AEEIEQTVEI LSRRRKNNPV LIGDPGVGKT AIVEGLAQRI
VNGDVPSTLA DRRVIALDLG ALVAGSKYRG EFEERLTKLL DEVRAHSDEL VLFIDELHTI
VGAGGGSEGS MDAGNLLKPA LARGDLHVIG ATTIDEYRRH IEKDAALERR FQPVMVSEPS
VEDTIEILRG LADVYEEHHG VRYQDEALIA AAELSDRYLT DRFMPDKAID LVDQAGARVR
LRTRTPGPDL RSKEEELARL RREKDAAVAA EDYEKANELK AAIAEAERSV SAAESADEPE
VTVTDIAEVV SRQTGIPVAD LTTEERERLL KLEDVLHKRV IGQEEAIVAV AEAVRRARAG
LKDPNRPIGS FLFLGPTGVG KTELAKALAE AVFGDEDRLI RFDMSEFQEK HTVSRLVGAP
PGYVGYDDAA QLTDKVRRQP YSVILFDEVE KAHPDVFNVL LQLLDDGRVT DSKGRTVDFK
NTIVIMTSNI GSDLILSAPD GDVDSITPKL MERLGQHFRP EFLNRIDETI VFHRLDRREL
RDIVELVLDG TRRLLHAQDI DLDITESAVD WLADHGYQPE YGARPLRRTV QKELDNKLSR
LLLDGGLEPG DTVRADADDH GLVLAAVEHR GDKTVEATV
//
