ID A0A366E5D7_9NOCA Unreviewed; 410 AA.
AC A0A366E5D7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=RNA polymerase ECF family sigma subunit {ECO:0000313|EMBL:RBO96999.1};
GN ORFNames=DFR74_1011018 {ECO:0000313|EMBL:RBO96999.1};
OS Nocardia puris.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=208602 {ECO:0000313|EMBL:RBO96999.1, ECO:0000313|Proteomes:UP000252586};
RN [1] {ECO:0000313|EMBL:RBO96999.1, ECO:0000313|Proteomes:UP000252586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44599 {ECO:0000313|EMBL:RBO96999.1,
RC ECO:0000313|Proteomes:UP000252586};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBO96999.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QNRE01000001; RBO96999.1; -; Genomic_DNA.
DR RefSeq; WP_067510259.1; NZ_QNRE01000001.1.
DR AlphaFoldDB; A0A366E5D7; -.
DR STRING; 1210090.GCA_001613185_03659; -.
DR OrthoDB; 9780299at2; -.
DR Proteomes; UP000252586; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR046531; DUF6596.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR47756:SF2; BLL6612 PROTEIN; 1.
DR PANTHER; PTHR47756; BLL6612 PROTEIN-RELATED; 1.
DR Pfam; PF20239; DUF6596; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000252586};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..78
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 109..161
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
FT DOMAIN 179..280
FT /note="DUF6596"
FT /evidence="ECO:0000259|Pfam:PF20239"
SQ SEQUENCE 410 AA; 44149 MW; E06D4559D5910286 CRC64;
MRTGPAVTLD AVYRAEFGRA VATVARLAGD IGLAEDAVQE AFADAMRTWP ERGWPANPGA
WITTAARHRA LDRLRRESAR ADKEYDAALL RAPVEEAEVS PVADDQLRMI FTCCHPALSP
PSQVALTLRL VCGLRTAEIA RLFLQPEHTV AQRLTRAKAK IRQAGIPLRV PPPHLLPDRV
PVVLSCVYLV FTEGYSATSG PVAVRDELCD EAIRLGRLVC GLLPEEPEAR ALLALMLLQD
SRRAQRRSAD GESVPLDEQD RARWDRAAIA AGLSCLHAAA AGGSGPYLAQ ARIAAAHATA
PSWGETDWHA VLSGYDELLG YADSPVIRVN RAVAVGFAHG FAAGLAALNE VAADPRLAGT
HVVPATRADL LRRAGRPREA AEHYRAALAT VGNDQTRRFL ARRLAEVEAG
//
