ID A0A366I1K3_9FIRM Unreviewed; 211 AA.
AC A0A366I1K3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:RBP59663.1};
GN ORFNames=DES36_11813 {ECO:0000313|EMBL:RBP59663.1};
OS Alkalibaculum bacchi.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Alkalibaculum.
OX NCBI_TaxID=645887 {ECO:0000313|EMBL:RBP59663.1, ECO:0000313|Proteomes:UP000253490};
RN [1] {ECO:0000313|EMBL:RBP59663.1, ECO:0000313|Proteomes:UP000253490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22112 {ECO:0000313|EMBL:RBP59663.1,
RC ECO:0000313|Proteomes:UP000253490};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBP59663.1}.
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DR EMBL; QNRX01000018; RBP59663.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A366I1K3; -.
DR OrthoDB; 9803687at2; -.
DR Proteomes; UP000253490; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:RBP59663.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253490};
KW Transferase {ECO:0000313|EMBL:RBP59663.1}.
FT DOMAIN 1..88
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 88..211
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 211 AA; 22126 MW; CBF6FD8A3E3E0DA4 CRC64;
MSVLEYIKNS VIAGDDEQVL KDVKMAIDMK EEPLSIINDG LIAGMNVVGA RFKVGDMFVP
EVLMAAQTMA AGVELVKPLI AAGDMPNKGT IILGTVKGDL HDIGKQLVAI MFDSNGYNVV
DVGFDVPTEK FVEAVKEHNA ELVGMSALLT TTMLEMKTVI DALEAAGLRD SVKVLIGGAP
VTAEFGEEIG ADGYAPDAGS ATELADTLLG I
//
