ID   A0A366IA04_9FIRM        Unreviewed;       433 AA.
AC   A0A366IA04;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=GHKL domain-containing protein {ECO:0000313|EMBL:RBP65374.1};
GN   ORFNames=DES36_107114 {ECO:0000313|EMBL:RBP65374.1};
OS   Alkalibaculum bacchi.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Alkalibaculum.
OX   NCBI_TaxID=645887 {ECO:0000313|EMBL:RBP65374.1, ECO:0000313|Proteomes:UP000253490};
RN   [1] {ECO:0000313|EMBL:RBP65374.1, ECO:0000313|Proteomes:UP000253490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22112 {ECO:0000313|EMBL:RBP65374.1,
RC   ECO:0000313|Proteomes:UP000253490};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBP65374.1}.
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DR   EMBL; QNRX01000007; RBP65374.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A366IA04; -.
DR   OrthoDB; 1776661at2; -.
DR   Proteomes; UP000253490; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253490};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        40..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        122..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        156..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          323..422
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   433 AA;  50025 MW;  43BF5B213BA2D507 CRC64;
     MDISLYNLVY IITNIFGTYI IYKFMSVFFN RKEVNRKIEL LSYLGYFIMI TIVYLFIKIP
     VVMMICNISA FIGLSLNYKA NIKKRILAVT YIYLISMCVE IIVIILLSGM RFTIFSENEY
     SISYSLIVLK VVTYIVVLVL GKFVNVKHSE SVPMSYWVCI ILMPVSSLYI ILILFQTQDI
     MLLQVIVGII FMLLINFATF YLFDRTSETL SNKMEAALLT KQNEYYNEQF NLMRNSLKST
     RQIKHDLINH LTVIYSLVHD NEIEHSLDHI SKMLYTIGEK KEHAHSGNII VDSILNFKLQ
     ELEQKNIKIA LDLNVPEEMD IPSFDMTIIL GNLLDNAVSA VCKLTEERYI NIIIKYDRGR
     FILNIDNPFE GKIAKEDDTF LTTKEDKANH GIGLQSIKTV LAKYNGTIDI SHNEKVFSVT
     LFMYIELSES NGC
//