ID   A0A366IAL0_9FIRM        Unreviewed;      1444 AA.
AC   A0A366IAL0;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Putative CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:RBP65390.1};
GN   ORFNames=DES36_107130 {ECO:0000313|EMBL:RBP65390.1};
OS   Alkalibaculum bacchi.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Alkalibaculum.
OX   NCBI_TaxID=645887 {ECO:0000313|EMBL:RBP65390.1, ECO:0000313|Proteomes:UP000253490};
RN   [1] {ECO:0000313|EMBL:RBP65390.1, ECO:0000313|Proteomes:UP000253490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22112 {ECO:0000313|EMBL:RBP65390.1,
RC   ECO:0000313|Proteomes:UP000253490};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBP65390.1}.
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DR   EMBL; QNRX01000007; RBP65390.1; -; Genomic_DNA.
DR   Proteomes; UP000253490; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253490}.
FT   DOMAIN          10..258
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          326..580
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          678..894
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
FT   REGION          1423..1444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1444 AA;  161501 MW;  71BB65F55D7C1DAD CRC64;
     MINKNRCYHL GLDVGSTTIK LVIFDEELNI VYSKYKRHLS NIQTTFKGII NEAYEELGNI
     NVTAAVTGSA GLSISNWLQI SFVQEVIAST KTVETLIPKT DVAIELGGED AKITYFDQSL
     EQRMNGTCAG GTGAFIDQMA TLLQTDASGL NELSKNHKVI YPIASRCGVF AKTDVQPLLN
     EGAAKEDIAA SVLQAVVNQT IGGLACGKPI RGNIAFLGGP LHFLSELRER FIETLQLREE
     QVIYPENAQL YVAMGAALSS KDEGKEISFS TINSKLEHID EFQHEEVQRL EPLFKDSKEL
     EEFYEKHNKY KVQRADLSSY KGNVFLGIDA GSTTSKAALI GDNGELLYTY YSSNLGSPLN
     QAIVILKDVY EVLPKDLKIS KSTVTGYGEG LIKSALRIDL GEIETMAHFK GAQHFLPQVD
     FILDIGGQDM KAMKIKDGVI DDIILNEACS SGCGSFLETF AHSLKLSVEE FAQEALMAKA
     PVDLGTRCTV FMNSRVKQAQ KEGADVGDIS AGLSYSVIKN AIQKVIKVRN PEELGKSIVV
     QGGTFYSNAV LRAFEKILGR DVIRPDISGI MGAFGAALIA KEKYVEGIES TILDEAQLQA
     FETDATLERC GKCGNNCLLT INNFSDGRRF VSGNRCERGV GIEQEQTTKK VPNMYDYKYK
     RLFNYNPLDK SEAIRGEVGI PRVLNVYENY PFWYRFFTEL KYRVVLSPRS SKKLYDKGME
     SIPSESVCYP AKIVHGHIMS LLEKDIDFIF YPCISYEEDD INGADNCYNC PIVMSYPETI
     KYNVDALKEK NINYMNPFLP LNDYNRLVER LIEEFAPLGI GEEEIRKACD LGWKEKDVYK
     EDVRKKSEEI LTYIEENDMT GIVLSGRPYH IDPEINHGLP NVITELGMAV LCEEGVSHLG
     EVKRPLRVLD QWKYHSRLYT AANFVAKQSN IELVQLTSFG CGLDAVTTDQ VHEILNEAGK
     IYTLIKIDEV SNLGAVKIRL RSLKAALEDK EELQYPKSST DVEYKRVSFT KEMKKTHTLL
     VPQMSPIHFD FINDAMEPSG YRVEVLPSVD YNAIDEGLKY VNNDACYPSI IAVGQLIAAV
     KSGKYDVNNI SFVMSQTGGP CRASNYVAFI RKALKDMDME HIPVISANLV GLESNPGFKI
     TLPLINRGMM AAVYGDLFQR VLYATRPYEK EKGSAERLYD SWRTKAKENT RSGNLFAFKR
     NIKKIVEDFD ALPLLNIEKP KVAVVGEILV KYHPTANNNL VQVLEDEGAQ VVVPDIIDFI
     LYCAYNNVFK YEKLAGTKKS MGNSLKGIKL IEWYRKSMKE ALKDSSRFNP PSTIDKKARK
     AEELISLGNQ GGEGWFLTAE MMELIEDGVE NIVCVQPFAC LPNHVMGKGM IKPIREKYPI
     ANIAAIDYDP GASEVNQLNR IKLMLSVAFR NLDKKNALKE ENVTNEATDE SRKKKLVLNE
     DFPR
//