ID A0A366IHH3_9MICO Unreviewed; 860 AA.
AC A0A366IHH3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Glycine cleavage system aminomethyltransferase T {ECO:0000313|EMBL:RBP71271.1};
GN ORFNames=DFO65_106114 {ECO:0000313|EMBL:RBP71271.1};
OS Brevibacterium celere.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=225845 {ECO:0000313|EMBL:RBP71271.1, ECO:0000313|Proteomes:UP000253509};
RN [1] {ECO:0000313|EMBL:RBP71271.1, ECO:0000313|Proteomes:UP000253509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3b_TX {ECO:0000313|EMBL:RBP71271.1,
RC ECO:0000313|Proteomes:UP000253509};
RA Lamendella R.;
RT "Freshwater and sediment microbial communities from various areas in North
RT America, analyzing microbe dynamics in response to fracking.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBP71271.1}.
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DR EMBL; QNSB01000006; RBP71271.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A366IHH3; -.
DR Proteomes; UP000253509; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:RBP71271.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253509};
KW Transferase {ECO:0000313|EMBL:RBP71271.1}.
FT DOMAIN 7..378
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 382..436
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 438..722
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 747..828
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 860 AA; 93091 MW; D68AB9ED15476775 CRC64;
MPTTTPRIVI IGAGIVGANL ADELAQLGWT NTLVLEQGPL DIPGGSTSHA PGLVFSSNGS
KSMTEFAQYT IEKYTGLKGS DGTGSFLPVG GLEIATTDER LQDLHRRAGW NRSWGVEAHV
VDTDECARLF PMLDRDKVLG GLLTPGDGLA LAAKGTQIVI ERARAAGVEF RDRTTVTDIE
VVGGKVRAVT VDGDERIPAD IVVSCAGFWG PNIGRMVGTP IPLLPLGHQF AWTTEVPSLV
AKKQGPAGAS APILRYQDKD LYYREWGDRI GIGSYAHRPM PVDLDELPRY APDEITKDRM
PSSLEFTPED FAGEWEATKE LLPELAQTQV QRGFNGIFSF TPDGGSLVGQ SREVDGFFVA
EAVWVTHGAG IAKAVAELIS QGYSNTDLSG CDLNRFEDAL TTPEYVSETS QQNFVEIYDV
LHPLQPRVSP RDLRLSPFHD RQVELGAYFL ETNGWERPHW YEANAGLLDE LPEEWAAPAR
DDWSSMFHSP IAAAEAWKTR TAVAMYDMTQ LKRFEVKGPG AGELLHGLTT SSMLRKPGAV
SYTLLLDEAG GITSDITVAI LDEQTYQVGA NSNIDFAYIS RKAREQSAAD PSKWATVRET
TAGTCCIGLW GPKARAVMSK VSSDDLSNAG LKYFQTKQIT IAGVPVTAMR LSYVGEFGWE
LYTSADLGHK LWDVLFAAGQ EHGIIAAGRE AFNSLRLEKG FRSFGTDMTS EHEPVQAGLG
FAVKASKTDD FVGKSALAAR AEAATTKLYC LVLDDRESVV LGKEPVYLGS GAEGSADGYV
TSAAYAYTVG RSIAYAWLPN SVEVGDSVEI EYLGRRLPAT VSVEPLYDPE MTRLRGDGEA
EPIPAVELVQ SNPDKVPAAV
//
