ID   A0A366IKF5_9MICO        Unreviewed;       377 AA.
AC   A0A366IKF5;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Putative naringenin-chalcone synthase {ECO:0000313|EMBL:RBP71464.1};
GN   ORFNames=DFO65_10563 {ECO:0000313|EMBL:RBP71464.1};
OS   Brevibacterium celere.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC   Brevibacterium.
OX   NCBI_TaxID=225845 {ECO:0000313|EMBL:RBP71464.1, ECO:0000313|Proteomes:UP000253509};
RN   [1] {ECO:0000313|EMBL:RBP71464.1, ECO:0000313|Proteomes:UP000253509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3b_TX {ECO:0000313|EMBL:RBP71464.1,
RC   ECO:0000313|Proteomes:UP000253509};
RA   Lamendella R.;
RT   "Freshwater and sediment microbial communities from various areas in North
RT   America, analyzing microbe dynamics in response to fracking.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBP71464.1}.
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DR   EMBL; QNSB01000005; RBP71464.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A366IKF5; -.
DR   Proteomes; UP000253509; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000253509}.
FT   DOMAIN          5..220
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          235..373
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        157
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   377 AA;  40239 MW;  2558076899ECF9AF CRC64;
     MAVTLRSLEV AVPETVLIQS EVRDVFAAQP GISDLARRLI GAAFNSSGID RRRSVVDEMS
     FSSRAESPLF FDPEAARILN PSTGTRNAVY VREAARLFVA AAGAALDACP DVEAGDVTHV
     ITVSCTGFFS PGPDYRIVRD LGLDPSVQRY HLGFMGCYAA FPALRQAKTI CDADPDAVVL
     VVSAELCSIH VRVSDDPDTI LGSSLFSDGA AAALITGRDP STGRGLRLDR FATVLTPVGE
     EAMAWNIGDH GFEMVLGTYV PKIIDEHIAG ALDPLLAADD SLTGSGYRRI EHWAIHPGGR
     SILDKVERRL GLDEDQLVHS RSVLREFGNM SSATVLFVLK RILDKPGSGD GERICSMAFG
     PGLTVETGLL TTVGANP
//