ID A0A366M9K3_9EURY Unreviewed; 227 AA.
AC A0A366M9K3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=polB2 {ECO:0000313|EMBL:RBQ22727.1};
GN ORFNames=ALNOE001_15680 {ECO:0000313|EMBL:RBQ22727.1};
OS Methanobrevibacter sp. NOE.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=2006182 {ECO:0000313|EMBL:RBQ22727.1, ECO:0000313|Proteomes:UP000253099};
RN [1] {ECO:0000313|EMBL:RBQ22727.1, ECO:0000313|Proteomes:UP000253099}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NOE {ECO:0000313|EMBL:RBQ22727.1};
RA Lind A.E., Lewis W.H., Spang A., Guy L., Embley M.T., Ettema T.J.G.;
RT "Genomic insight into two independent archaeal endosymbiosis events.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBQ22727.1}.
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DR EMBL; NIZT01000047; RBQ22727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A366M9K3; -.
DR Proteomes; UP000253099; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 1.10.132.60; DNA polymerase family B, C-terminal domain; 1.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR042087; DNA_pol_B_thumb.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR PANTHER; PTHR10322; DNA POLYMERASE CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR10322:SF23; DNA POLYMERASE DELTA CATALYTIC SUBUNIT; 1.
DR Pfam; PF00136; DNA_pol_B; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotidyltransferase {ECO:0000313|EMBL:RBQ22727.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253099};
KW Transferase {ECO:0000313|EMBL:RBQ22727.1}.
FT DOMAIN 27..202
FT /note="DNA-directed DNA polymerase family B
FT multifunctional"
FT /evidence="ECO:0000259|Pfam:PF00136"
SQ SEQUENCE 227 AA; 25925 MW; E195DD6D5CE7A1DD CRC64;
MVTESNEQLA LEKKIKSQAN KFLVDFNGTL PESMELEYEG FYRRGFFVSK KRYAVVEDGA
IIAKGLELVR RDWAPVAKDT QQGILLAILK DGDVDKAVEI IKKILKKVKT GTVPMKDMII
HTQITKKLDA YKQIGPHVVA AQRLEKKGMK IDKGTIIQYV VVKGKGPISQ RAIPFEDAEK
YEYDPDYYID NQIIPAVSRI MESFGYTQEK IKELGEKERQ KTLDSFF
//
