ID   A0A366RJH1_9HYPO        Unreviewed;       827 AA.
AC   A0A366RJH1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   03-MAY-2023, entry version 14.
DE   RecName: Full=Probable vacuolar protein sorting-associated protein 16 homolog {ECO:0000256|PIRNR:PIRNR007949};
GN   ORFNames=FIESC28_06519 {ECO:0000313|EMBL:RBR17283.1};
OS   Fusarium coffeatum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium incarnatum-equiseti species complex.
OX   NCBI_TaxID=231269 {ECO:0000313|EMBL:RBR17283.1, ECO:0000313|Proteomes:UP000253153};
RN   [1] {ECO:0000313|EMBL:RBR17283.1, ECO:0000313|Proteomes:UP000253153}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FIESC_28 {ECO:0000313|EMBL:RBR17283.1,
RC   ECO:0000313|Proteomes:UP000253153};
RA   Gardiner D.M.;
RT   "Fusarium incarnatum-equiseti species complex species 28.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for vacuolar protein sorting. Required for vacuole
CC       biogenesis, stability and to maintain vacuole morphology.
CC       {ECO:0000256|PIRNR:PIRNR007949}.
CC   -!- SIMILARITY: Belongs to the VPS16 family.
CC       {ECO:0000256|ARBA:ARBA00009250, ECO:0000256|PIRNR:PIRNR007949}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBR17283.1}.
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DR   EMBL; QKXC01000134; RBR17283.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A366RJH1; -.
DR   OrthoDB; 1110811at2759; -.
DR   Proteomes; UP000253153; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0007033; P:vacuole organization; IEA:InterPro.
DR   Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR016534; VPS16.
DR   InterPro; IPR006925; Vps16_C.
DR   InterPro; IPR038132; Vps16_C_sf.
DR   InterPro; IPR006926; Vps16_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12811; VACUOLAR PROTEIN SORTING VPS16; 1.
DR   PANTHER; PTHR12811:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG; 1.
DR   Pfam; PF04840; Vps16_C; 1.
DR   Pfam; PF04841; Vps16_N; 1.
DR   PIRSF; PIRSF007949; VPS16; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|PIRNR:PIRNR007949};
KW   Transport {ECO:0000256|PIRNR:PIRNR007949}.
FT   DOMAIN          8..410
FT                   /note="Vps16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04841"
FT   DOMAIN          503..811
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
FT   REGION          805..827
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   827 AA;  93166 MW;  CC6AA7137E67AD39 CRC64;
     MDTLHARADW ESVGDRWFRK TQQYTAVFDQ DLDLDNYIVA GAPYAGALAL WRDDTKLVAY
     QPGRSAKPAI DIYSLAGKKL RSIPWDKGSI KGLGWSENET LLVVTADGIV RCYDLQGDFT
     QFSLGHGADN YSVESCRFYD HGMVALLGNN TLITVSSYTE PRPKALAQTP EAEIHAWSII
     SPNHTLSRSV EVLLSVDKTV YVVDATDCED RFLDIGPFSH ISVSPDGRYV NLYAKNGKAH
     VISSDFQERL FEHDSNSQTP PLYVEWCGSD ALIAWEDEVH IIGPGETSSS YIYDSTRVHV
     VSEHDGARLI TNDFCEFLER VPRDTLEVFG QSSDSSPASI LLDAVGQLEL QSPKADDYIQ
     LIRPNLTGAV DTCVNAAGRE YDTHWQKRLL KAASFGKSVL DIYNSDDFVD MCETLRVLNA
     VRYYEIGMPL SFEQYHRLTP ESLIRRLLNR HEYLLALKIT GYLKLPTDRI YVHWASSKVR
     VGGEDDDTIC RLIVERLSGK PGISFEEIAR AAYQEGRGRL ATELLNHEPR GGRQVPLLLS
     MEEDELALDK AIESGDTDLI LTVLLQLRKK LPLAAFFRVI NARPTATALV EALAMEEGDN
     TLLKDLYYQD DRRTDGANVF IRESLKQPDA RTTSDKLALA AKLLADSKES SFEVHALKEA
     TTLLRMQEAF DRDLTDTFTG LSVHETMFKL IRLGYQGRAK KIQSEFKVPE KVAWWIRLRA
     LVAKRDWSEI EEISKTRRSP IGWEPFFNLT LQAGNPRVAS VFIPKCTGVE TGETITMYEK
     CGMRVKAAQE AVRLKDSESW ERILEEAGRT TQEGREIERL GQSAFKK
//