ID A0A366RRB8_9HYPO Unreviewed; 1028 AA.
AC A0A366RRB8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Sodium/calcium exchanger membrane region domain-containing protein {ECO:0000259|Pfam:PF01699};
GN ORFNames=FIESC28_05486 {ECO:0000313|EMBL:RBR19659.1};
OS Fusarium coffeatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium incarnatum-equiseti species complex.
OX NCBI_TaxID=231269 {ECO:0000313|EMBL:RBR19659.1, ECO:0000313|Proteomes:UP000253153};
RN [1] {ECO:0000313|EMBL:RBR19659.1, ECO:0000313|Proteomes:UP000253153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FIESC_28 {ECO:0000313|EMBL:RBR19659.1,
RC ECO:0000313|Proteomes:UP000253153};
RA Gardiner D.M.;
RT "Fusarium incarnatum-equiseti species complex species 28.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000256|ARBA:ARBA00008170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBR19659.1}.
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DR EMBL; QKXC01000112; RBR19659.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A366RRB8; -.
DR OrthoDB; 5482417at2759; -.
DR Proteomes; UP000253153; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 2.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR PANTHER; PTHR12266:SF0; MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN; 1.
DR PANTHER; PTHR12266; NA+/CA2+ K+ INDEPENDENT EXCHANGER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 786..806
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 818..842
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..868
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 880..897
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 917..943
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 963..988
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1000..1024
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 133..271
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 854..1015
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 307..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1028 AA; 112326 MW; F02123EBD3F5F1C7 CRC64;
MINITPRGLV RPNHDIIERR DTASKRFIRG SRLKSRPFYT TLFLLSVLTA YSFLSHTTFA
QSVSKHAIDS HQLFKRSSST EPPQCSQVHD AQDKCAFVRK YCTDDDAGLV PYTELYYCTF
GSVRPIAFSI LVVWLGLLFT TIGIAASDFF SVNLGTIATV LGLSESLAGV TFLAFGNGSP
DVFSTFAAMG SNSASMAVGE LIGAASFITG VVAGSMALVR EFRVDRKTYT RDICFFIFAV
IFTMIFLADG HLHLWECWAM IGYYALYVVT VVTWHWYSMR HKARQRREGE ARSHVYTALV
QSGDELAGEP YRDDVDDAGS ASRTAYSTPP DISLLEAGPR IEVEGTLQAE DSDTSSEDHD
RMVAAEVASS MRVLRGRGTR RNTMTPIRPS LVGALEFRSA LAQLQREGNL QLSTIPGRSY
SDHHVHRRRQ TTTTILGSAR SDDQLASSHD GHSSRRNRAL SSGDQPVGTA AHPDWSIPGH
DRSERNLSIP GSPASGTRAS SPNPSHTVGG NLAAPLVGPS GTTYDAPTED TRRHMLTPEL
HLQIPSRRSS CSDRSSPSTP FPMYTDSPAL LTPNYHNDPI EFVSPGGVSP STVPLGSTSR
ETPFADLQFT IDVPSRPVRW WPYAVLPPPH ILLATLFPTL QGWKEKTAWD KFVSAISVPS
IFLLVVTLPV VDSETTDGES SILETIVDPY DHHSPGHLAP PISVEHSSIE PEGETEWQRY
RRHTLVSRGN SHTGSGAPPS SAHAPGEEHH GAPQLSLGPP AIVTKPASDF LSSSSAKNDC
TGWNRWLVAL QLFTGPQFAV LILWANTLED WENPRKTLIR MFLYTLLGSL ILLGILIVFT
SQDRAPRYHY MLCFMGFFIS IAWISTIAGE VVGVLKTVGV ILNISEALLG LTIFAAGNSV
GDLIADITVA RLGYPVMALS ACFGGPMLNI LLGIGIGGAM MMIKKANKKH HKNPSSPIKY
KPYRIQVNGT LLISAITLLV TLIGLLIVVP WNKWILSRKI GWGLIILWAV STVVNVVVEV
TGVWGQMA
//
