ID A0A366ZJP1_9ACTN Unreviewed; 1717 AA.
AC A0A366ZJP1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DQ238_17220 {ECO:0000313|EMBL:RBY76431.1};
OS Geodermatophilus sp. TF02-6.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Geodermatophilus.
OX NCBI_TaxID=2250575 {ECO:0000313|EMBL:RBY76431.1, ECO:0000313|Proteomes:UP000253027};
RN [1] {ECO:0000313|EMBL:RBY76431.1, ECO:0000313|Proteomes:UP000253027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TF02-6 {ECO:0000313|EMBL:RBY76431.1,
RC ECO:0000313|Proteomes:UP000253027};
RA Ennis N., Dharumadurai D., Sevigny J., Hall J., Simposon S., Morris K.,
RA Thomas W.K., Tisa L.S.;
RT "Genome Sequence of Geodermatophilus sp. TF02-6.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RBY76431.1}.
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DR EMBL; QOHF01000020; RBY76431.1; -; Genomic_DNA.
DR OrthoDB; 163538at2; -.
DR Proteomes; UP000253027; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 3.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR Pfam; PF13466; STAS_2; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 3.
DR SMART; SM00387; HATPase_c; 2.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 3.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS50801; STAS; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RBY76431.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000253027};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 355..573
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 629..744
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 753..823
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1611..1717
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT MOD_RES 677
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1717 AA; 180370 MW; A456BD14326A5D35 CRC64;
MTGQAPERSL FAGGGEVGRA MAERDWAQTP LGLPETWPPE LRNVVRIVLT SRFAMWAAWG
PDLTFFYNDA YRDDTLQAKH PWALGRPARE VWAEIWDDIA PRIRSVLDTG VATWDEDLLL
FLERNGYPEE TYHTFSYSPL SGPDGRTEGM LCVVTENTER VLGERRMAHL RDLAAAIGTS
RTEADVLAAV GEQLGRNRAD LPFSATYLVD GSGTARLGCA AGIEPGSPAV PAVLTPDDGD
PVWPLARLLA GEPVLVEDLA DRFPDLPTGA WDLPPRQAAA LPIASGVQDR GAVAGFLVVG
LNPHRRSDDA YRGFLELVAN QIASALGNAG SYEAERRRAE ALAELDRAKT DFFSNVSHEF
RTPLTLIAGP VAELHRSPAA DADPRVREEL EVIERNAQRL RKLVDTLLDF SRIQAGRIDA
RFEPVDLAAT TAELASVFRS AVVRAGLAFT VDCPPLEAPV HVDRDMWEKV VLNLLSNALK
YTFTGGITVR LRRDGGTARL TVSDTGTGIP AEELPRLFER FSRVRGARGR SGEGSGIGLA
MVRELVGLHG GTIDVESTLG AGSTFTVTLL LGAAHLPAER LAEPAPDAPA VSPAAVPFVT
EALRWLPGDD GDAAGTVAPS PAPGTAAGRV LVADDNADMR EYVLRLLAPR YDVRAVADGS
SALEAALADP PDLVVSDVMM PGLDGVQLLA ALRADVRTAR VPVVLLSARA GEEAAVEGLA
AGADDYLVKP FSAQELLARV GAHLQLGRVR RAAEERFTAV ADVAPALIWV ADPEGRRVFV
NRGWTEFTGR PACEELGTGW EAGIHPEDRD RYARVVAAAT AQRSGWEVDV RLRRTDGAHH
WLLERAAPIG ADEDFAGYVG SCTDINARTR ETARQTLLAE VGTALDRETT VDGQVGALAR
LLVDRRLGDI CTVRLVGEDG RLRYAGIAGL DAATEAALAA LDPDAGLARE VLATGRPVRR
APLPAGWPLR ADAPEGERAE TDRRLGMRSG LVVPLTVRGR VLAVLALARR GDAPPVDDDD
RVLAEEIAAR AALAVDNAVL LADERAAAHR LALLQRATAE LSAATTPVEV ARAAADHLRA
LTGPQSRVAV YELDAAHRAL VALAIDGASA AGERAWRVLP LSAPLIATAA VAERRAVWVE
DVAASPPGAQ LPPELAESAR GFGLAAHVAL PLAVAGRVVG VVAIAWSTVQ RFSATDRGML
LAVAEQCAQA LDRARLFRAE RGIAETLQRS LLPAQLPRLD RLALAAHYLP GAEGTQAGGD
WYDVVELAGS RVAIAVGDVV GQGPAAAAVM GQLRSALSAA LLQGCGPAEA LELLDRFAVR
LPGALASTAA CLVVDAAAGT VRWARAGHLP PLLVTAGGAR LLDGAGSGAV LGAPGRRPYT
EGSADIAPGA TLLLYTDGLV ERRGELLDDG LGRVCDAAGR YAAADPARLT ARLLAEVLAD
TDQPDDVALI AARLLPGPLA ERLPADPVRL SAVRRAVARW TAAAGLPEET AEDLQLALGE
ALANAVEHAY GSDGVAGSSG GGQCSYGVSR DADGGVRVEV RDTGAWRPPP ENRGSRGRGL
ELISTLATDV EVDHGPGSPG TTVRFRVPPA PVAPGARPPR AAYPAADGGA ARLLVHDEPG
GLRVQVLGEV DLATAAAVRE EVLGCLDRLP PGSRATLDLR STGHLASAGV GVVLEALTRA
GQAGVDLRVH TAPATPPARI LALAGVDDSA ARALPLR
//
