ID A0A367EI39_9ACTN Unreviewed; 1316 AA.
AC A0A367EI39;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=AfsR/SARP family transcriptional regulator {ECO:0000313|EMBL:RCG16870.1};
GN ORFNames=DTL70_27960 {ECO:0000313|EMBL:RCG16870.1};
OS Streptomyces diacarni.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2800381 {ECO:0000313|EMBL:RCG16870.1, ECO:0000313|Proteomes:UP000252914};
RN [1] {ECO:0000313|EMBL:RCG16870.1, ECO:0000313|Proteomes:UP000252914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LHW51701 {ECO:0000313|EMBL:RCG16870.1,
RC ECO:0000313|Proteomes:UP000252914};
RA Li L.;
RT "Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp. nov.
RT from marine sponges.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCG16870.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QOIN01000057; RCG16870.1; -; Genomic_DNA.
DR OrthoDB; 499349at2; -.
DR Proteomes; UP000252914; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000252914};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 248..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 863..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1242..1290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..280
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..347
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..885
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1316 AA; 140368 MW; 072CEA09993EA79F CRC64;
MRYLILGASE ARDDAGRPVP LGGQRLRALL AALALRAHSR APASPQALID DVWADAYPDA
LPEDAPAALQ ALVGRLRRAL GRDAVESLTG GYRLRLDPER DEVDLLRFER LATEGERALE
EGDAERAARI LREALALWRG PALADLPDRV AVAARMEALR HAALQRRLAA DLALGHAARV
LPELRQLAPE HPLDEPLQVL HLRALHESGR TAEALAGYES VRRGIASRLG ADPGAELRAL
HAELLRASTP SGTDTSSTPA PVPVPGPVPV PGPGPGPGPG PVSDEGTSGT GRSVRTARTG
ETRTPVPAPG DRAAPGDRAA PEGDHAHPLP PPPGRDAHPP PPESEAEPAP TRGARRTPTA
DGAKPTPGGG RPTPTSEGQA PIPEGHTPTV EGQTPLPEGR GPARPPGNLR ARLTSFVGRE
TDIATLSADL AASRLVTLTG PGGSGKTRLA EQVAATTGAA DPTPHPDGTW FVELAPLDHP
TAVPGAVLSA LGRRVTALST AATEGARALN GQQDATALLV EHLQHRTPLL VLDNCEHVVH
AAATLAETLL AHCPGLTVLA TSREPLGVPG EAVRPVEPLP PAPAHRLFAD RAAAARPGFR
PSEDAEAVAE ICRRLDGLPL AIELAAARLR SLTPRQIADR LDDRFRLLTS GSRTVLPRQQ
TLRAVVDWSW DLLDERERTT VRRLSVFAGG CTLSAAEHVC ADESPPAPGP PPSGHIHPDD
VLDLLSALVD KSILVADQPP ALTGTGVRYR MLETIHDYAR ERAAEHPEER DEAEARHTAQ
ILRFATAAEP RIRSAEQLSW LPRVEADLDN IRAALHRSLY QRDHETVVAL VRAAGWFWWL
RNFRDEGARW VEAALTLLPT SPERRGAERR GAERRDDGKR EDERRDEDDG EDENEELLVR
ELQLLDYFLL SEHRTQELVT EPYHRAVAAQ LVATFREPGP ASARFPGMLW PFAGFLLEGG
QGVAPLMREL VANCRRYSGP WELAVALLFR AHIRLDTPGG LPRLKEDLPE ISALAESTGD
RWLLSQLCGL RAEIAIQEGC YEDARAECET AMRYAQQLGA LTEMPVLLVR IADIWYRQGD
TKQADQLAQR ALEDGDRLGV RDAPTLAVFV RAMAAVEEDD IARARELYRQ AEKYASVGSL
PAVFEVPLRV LDARITACEG DELIPEALRK INAALHAGLA VAVPETVTGN ALLTAGFILL
RAGRSALAVQ LADAAGATRG DLPASVPELR LDGTIRAYSA GAAADASGAD PDGTSDADPD
GTSVPDSDGA SDDGRDGAFD DGPEAAGAPL TLAEAAARLD KLCDQLAAES GAPPTG
//
