ID A0A367EYM8_9ACTN Unreviewed; 325 AA.
AC A0A367EYM8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=D-2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:RCG23121.1};
GN ORFNames=DTL70_15730 {ECO:0000313|EMBL:RCG23121.1};
OS Streptomyces diacarni.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2800381 {ECO:0000313|EMBL:RCG23121.1, ECO:0000313|Proteomes:UP000252914};
RN [1] {ECO:0000313|EMBL:RCG23121.1, ECO:0000313|Proteomes:UP000252914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LHW51701 {ECO:0000313|EMBL:RCG23121.1,
RC ECO:0000313|Proteomes:UP000252914};
RA Li L.;
RT "Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp. nov.
RT from marine sponges.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCG23121.1}.
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DR EMBL; QOIN01000043; RCG23121.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367EYM8; -.
DR OrthoDB; 4324715at2; -.
DR Proteomes; UP000252914; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000252914}.
FT DOMAIN 108..290
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 325 AA; 34141 MW; A21E9F91FD6A8C2E CRC64;
MTTAGADPLR IGHELNGAVV TVDPALPDRV REGVEQIVGR PVGTGRGPRV HIGPHFPELA
EGERLLWVHS TNAGVDALLK ARTPWPREVL LTRTVGRMGE RIGQYVLAWV LAELQNVPAF
LEQHARRTWH GLPTELADGA VAVVLGAGRI GTAIGTALQQ CGVHTVGVAR SPREMPGFDS
VVPLGVPEKP GGGPSRELAD VLAKARWVVN ALPLTPQTSG LVGAGLLGAL RGATFLNVGR
GETVLTDALA RALDEGTVGH AVLDVLPEEP AAPADPAWDL PRTTLTCHSA GPTTHEDVTA
DFRAAWQALR AGELPTLTVR VSAGY
//
