ID   A0A367F2X3_9ACTN        Unreviewed;       500 AA.
AC   A0A367F2X3;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=FAD-binding protein {ECO:0000313|EMBL:RCG24708.1};
GN   ORFNames=DTL70_10190 {ECO:0000313|EMBL:RCG24708.1};
OS   Streptomyces diacarni.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2800381 {ECO:0000313|EMBL:RCG24708.1, ECO:0000313|Proteomes:UP000252914};
RN   [1] {ECO:0000313|EMBL:RCG24708.1, ECO:0000313|Proteomes:UP000252914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW51701 {ECO:0000313|EMBL:RCG24708.1,
RC   ECO:0000313|Proteomes:UP000252914};
RA   Li L.;
RT   "Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp. nov.
RT   from marine sponges.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCG24708.1}.
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DR   EMBL; QOIN01000039; RCG24708.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A367F2X3; -.
DR   OrthoDB; 9813348at2; -.
DR   Proteomes; UP000252914; Unassembled WGS sequence.
DR   GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252914}.
FT   DOMAIN          19..438
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
FT   REGION          474..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   500 AA;  51155 MW;  4F6D7ABB2CDBC1AE CRC64;
     MSGPDAAGDR TARDEASVDL VVAGAGGGLA GALAAAQAGL SVLVVDPDAH FLRGNNTSMS
     TAMIPGAGSR WQREAGVEDG PQRFLADIEA KTHGTADPAL AAALARISAP LVEWLADGVG
     LPLGLVRDFS YPGHSADRLH TVEGRHGSTL LRHLHERVRA SSRADLLTPA RLVDVTRDAA
     GRVDGAVVED PGGHRETVST RAVLLATGGH GADRERVARY LPGIAAADYY GGQFARGDGL
     DIGLAHGGRA AYLDAYQGHA ALARRSRTLV GWATVMHGAV MVDAGGRRFG DETSGYSEYA
     AALAQQPGAR GWIVLDGRIR DLCLPFTDFR QTVEAGCLTW ADDVEELAAR TGCAAAALDE
     ALSGQAAVAT GVAARDRFGR TFFEEPLRPP YAAVEVIPAL FHTQGGLVVD GHARVLGGDG
     TPVDGLFASG GAAHGISGHG ADGYLAGNGL LPALGLAWQA ATTLSTTAAP TATAPPVAVA
     DPPTAAAETA RTAPTVPDAR
//