ID   A0A367F574_9ACTN        Unreviewed;       261 AA.
AC   A0A367F574;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Regulator of SigK {ECO:0000256|ARBA:ARBA00030803};
DE   AltName: Full=Sigma-K anti-sigma factor RskA {ECO:0000256|ARBA:ARBA00029829};
GN   ORFNames=DTL70_09080 {ECO:0000313|EMBL:RCG25526.1};
OS   Streptomyces diacarni.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2800381 {ECO:0000313|EMBL:RCG25526.1, ECO:0000313|Proteomes:UP000252914};
RN   [1] {ECO:0000313|EMBL:RCG25526.1, ECO:0000313|Proteomes:UP000252914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW51701 {ECO:0000313|EMBL:RCG25526.1,
RC   ECO:0000313|Proteomes:UP000252914};
RA   Li L.;
RT   "Streptomyces reniochalinae sp. nov. and Streptomyces diacarnus sp. nov.
RT   from marine sponges.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC       Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCG25526.1}.
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DR   EMBL; QOIN01000036; RCG25526.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A367F574; -.
DR   OrthoDB; 153510at2; -.
DR   Proteomes; UP000252914; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.10.1320; Anti-sigma factor, zinc-finger domain; 1.
DR   InterPro; IPR018764; Anti-sigma_K_RskA.
DR   InterPro; IPR041916; Anti_sigma_zinc_sf.
DR   PANTHER; PTHR37461; ANTI-SIGMA-K FACTOR RSKA; 1.
DR   PANTHER; PTHR37461:SF1; ANTI-SIGMA-K FACTOR RSKA; 1.
DR   Pfam; PF10099; RskA; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000252914};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          70..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   261 AA;  27627 MW;  67E9BAAA50CBA489 CRC64;
     MTTMELHTLT GAYAVHALQP DEEAAFERHL GDCAACSVEV AELRATAARV GLALAEQPTP
     RMRAEVLHRI GEVRQEPPPR QQPPSDTPRA DVPRGVRRRA ARTWPTFALA ACLAVAAGFG
     GVAVWQYQRA EQAQESGQSA QNRAARLAEV LSAPDARTVP AKDLPGGGSG TVVVSRDQDR
     AAFVASRLPQ APEGKTYQLW YADHGTMRSA GLMDASSDDA WLLEGPLGDA SGMGVTVEPS
     GGSTKPTSEP VVLVNFPAQQ A
//