ID A0A367FE52_9ACTN Unreviewed; 312 AA.
AC A0A367FE52;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=peptide chain release factor N(5)-glutamine methyltransferase {ECO:0000256|ARBA:ARBA00012771};
DE EC=2.1.1.297 {ECO:0000256|ARBA:ARBA00012771};
GN ORFNames=DQ384_22920 {ECO:0000313|EMBL:RCG28604.1};
OS Sphaerisporangium album.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Sphaerisporangium.
OX NCBI_TaxID=509200 {ECO:0000313|EMBL:RCG28604.1, ECO:0000313|Proteomes:UP000253094};
RN [1] {ECO:0000313|EMBL:RCG28604.1, ECO:0000313|Proteomes:UP000253094}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCTCC AA 208026 {ECO:0000313|EMBL:RCG28604.1,
RC ECO:0000313|Proteomes:UP000253094};
RA Li L.;
RT "Sphaerisporangium craniellae sp. nov., isolated from a marine sponge in
RT the South China Sea.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-
CC methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release
CC factor] + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42896, Rhea:RHEA-
CC COMP:10271, Rhea:RHEA-COMP:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:61891; EC=2.1.1.297;
CC Evidence={ECO:0000256|ARBA:ARBA00000932};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCG28604.1}.
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DR EMBL; QOIL01000013; RCG28604.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367FE52; -.
DR OrthoDB; 9800643at2; -.
DR Proteomes; UP000253094; Unassembled WGS sequence.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004556; HemK-like.
DR InterPro; IPR022446; MeTrfrase_put.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR00536; hemK_fam; 1.
DR NCBIfam; TIGR03704; PrmC_rel_meth; 1.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000253094}.
FT DOMAIN 131..206
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 312 AA; 32443 MW; 38A2E9BA54B866AE CRC64;
MSVSPASLPE LPELPELPAP SEAVIVTRLR AAGCVFAEDE ARLLVSSART PADLSAMVER
RVAGLPLEHV LGWAEFCGLR VTVAPGVFVP RRRSEFLVTQ AVEHTRRAAL RSGAPSPDPS
AGRLIPLRRP VVVDLCCGTG ALGAALAQAL GPVELHAADI DPAAVECARD NLAALGGHVY
AGDLYEPLPA MLRGRVDILV ANAPYVPTGA VGLLPSEARD HEPLVALDGG RDGLDVLRRV
IAEAPRWLAP GGILLVETSE RQAPSLVEIV HGAGATGGSG GAARDGVVAR VVEDDEMDAT
AVVFVRPEGR SV
//
