ID A0A367FK08_9ACTN Unreviewed; 1388 AA.
AC A0A367FK08;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DQ384_15950 {ECO:0000313|EMBL:RCG30239.1};
OS Sphaerisporangium album.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Sphaerisporangium.
OX NCBI_TaxID=509200 {ECO:0000313|EMBL:RCG30239.1, ECO:0000313|Proteomes:UP000253094};
RN [1] {ECO:0000313|EMBL:RCG30239.1, ECO:0000313|Proteomes:UP000253094}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCTCC AA 208026 {ECO:0000313|EMBL:RCG30239.1,
RC ECO:0000313|Proteomes:UP000253094};
RA Li L.;
RT "Sphaerisporangium craniellae sp. nov., isolated from a marine sponge in
RT the South China Sea.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCG30239.1}.
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DR EMBL; QOIL01000008; RCG30239.1; -; Genomic_DNA.
DR OrthoDB; 9810730at2; -.
DR Proteomes; UP000253094; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 7.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.1530; -; 4.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00672; HAMP; 4.
DR Pfam; PF18947; HAMP_2; 3.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00304; HAMP; 7.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 3.
DR PROSITE; PS50885; HAMP; 7.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000253094};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 106..160
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 200..252
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 292..344
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 384..436
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 476..528
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 568..620
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 660..712
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 965..1197
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1256..1373
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 886..934
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1306
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1388 AA; 150373 MW; 4953427512F948B0 CRC64;
MKGTPTAEPV PERCYTESEL RPLLETLITW RDGDFRRRVP HAPHGILSEI RLLVNEVADR
REHLANELLR VRREVVKEGR FGVRLTPGPG VGSWAESVDS VNALIDALVG PVSSAADVLD
AVAQGDLSRR IDMDRTSRGE VRRLGKAING MVDQLSLFSS EVTRVAREVG SEGQLGGRAN
LRGMSGSWRD LTEAVNTMSS RVSAQVRDIA VVTTAVARGD LSRKVTVDAV GEMLELKNTV
NTMVDQLSAF AEEVTRVARE VGTEGELGGQ ARVRGVSGVW KDLTDNVNVM ASNLTSQVRN
IATVATAVAQ GDLSKKITAD AQGEMLQLKE TLNTMVDQLS MFADEVTRVA REVGTEGQLG
GRADVKGVSG VWKDLTDNVN SMANNLTYQV RNIAQVTKAV AGGDLSKKID VDAQGEMLEL
KSTINTMVDQ LSSVASEVSR VAREVGSEGQ LGGQAQVRGV SGVWKDLTDN VNFMANNLTS
QVRQIAAVSN AVVQGNLSKK ITVDAQGEIL QLKDTVNTMV DQLSMFADEV TRVAREVGTM
GQLGGQARVR GVSGVWKDLT ESVNELAGNL TYQVRNIGEV TTAVAKGDLS RKIDVDAQGE
ILVLKTTINR MVDQLSSFAS EVTRVAREVA SDGRLGGQAR VEGVEGTWKQ LTESVNELAG
NLTTQVRAIA EVTSAVARGD LTRSISVEAQ GELADLKDNI NTMVSNLVAT TKANQEQDWL
KSNLARVSRL MQGHRDLMEV GKLIMSELTP LVTAHHGAFY MVSSPRDTEL RLIAGYGVRP
GDGLGPRERF AFGQGIVGQA AAEGRPIVLD NVPSDYLTID SGLSSSTPAQ IVVLPVIFED
QVLGVMELAS FSRFGEVHLA FLNQLVETIG VTMNTIIANS RTEGLLAESQ RLTTELRERS
DELQRQQEEL RRSNAELEDK AALLAKQNRA IEIQNFQIEQ ARRTLEERAE QLAVSSRYKT
EFLANMSHEL RTPLNSLLVL AKLLTENSEG NLTAQQVEFA KTIHGAGSAL LQLINDILDL
SKVEAGRMDI HPQQISMPKL VEYVEATFGP LAQDKGLSFS VELDPAVPDE LRTDEQRLQQ
VLRNLLSNAV KFTPKGEVRL DITRAAGVPY IDETLRGSDD ILSFSVIDTG IGIAPEKLDV
VFEQFRQADG TTSRKYGGTG LGLSICREIA RLLGGEIHAK SEPGRGSTFT LHLPISYSGP
LANGDGGAAV LDTPQEASLE LTASDVLPEL PAIAEEPPLP HTPVAWQGDD PLNGAKILIV
DDDIRNVFAL TSVLERHGAT VVYAENGLEG IDQLERNDDV ALVLMDIMMP EMDGWATTST
IRRMPQFADL PIIALTAKVM HGDREKSIAS GASDYVPKPV DVDRLLERLR GWLTRGRVAS
GEGREGRG
//
