ID A0A367G2T2_9FIRM Unreviewed; 559 AA.
AC A0A367G2T2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=2-hydroxyglutaryl-CoA dehydratase {ECO:0000313|EMBL:RCH45017.1};
GN ORFNames=C4885_14835 {ECO:0000313|EMBL:RCH45017.1};
OS Subdoligranulum sp. APC924/74.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Subdoligranulum.
OX NCBI_TaxID=2086273 {ECO:0000313|EMBL:RCH45017.1, ECO:0000313|Proteomes:UP000253465};
RN [1] {ECO:0000313|EMBL:RCH45017.1, ECO:0000313|Proteomes:UP000253465}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APC924/74 {ECO:0000313|EMBL:RCH45017.1,
RC ECO:0000313|Proteomes:UP000253465};
RA Fitzgerald B.C., Shkoporov A.N., Ross P.R., Hill C.;
RT "Complete genome sequencing of Faecalibacterium prausnitzii strains
RT isolated from the human gut.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCH45017.1}.
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DR EMBL; PSQF01000122; RCH45017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367G2T2; -.
DR OrthoDB; 9778513at2; -.
DR Proteomes; UP000253465; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 3.40.50.11890; -; 1.
DR Gene3D; 3.40.50.11900; -; 1.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR InterPro; IPR010327; FldB/FldC_alpha/beta.
DR NCBIfam; TIGR00241; CoA_E_activ; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR PANTHER; PTHR32329:SF2; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 1.
DR Pfam; PF06050; HGD-D; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000253465}.
FT DOMAIN 303..551
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
SQ SEQUENCE 559 AA; 59221 MW; FF849E45BD93F9CE CRC64;
MSKTIYYACK YAPLELFAGY GATFSALDPL AESFSCAERC AHANLCGYAK AVLEQVEQSG
IRALVLTNCC DAMLRVYDVL AASGKMEFLQ LLPVPHQSTP ATRARFARDL RRLADALQRY
TGQEFDAQRA HAFFVHKPHA EGPHLTLLGA HGGSVLYDTV QKAFALPVVD ATCTGNRELA
DVAPAALEDF LPGYAAALLG QMPCMRMDAP VSERAALVDG QTVGIVYHTV QFCDYYAPGL
TAPEQFHLPV LKIETDCSRQ TFTSGGGQLS TRLGAFAESL NAVPDTENKE APAMNTNAQY
AAGIDSGSAS TDAVILDRSG KICGWAIVPT GAGAATGARQ ALEQALTMAG IAESDLGSKV
YTGYGREFLG DDGAAVTEIT CHARGAHHLD PAVRTVIDIG GQDSKVIRLS ESGAVETFAM
NDKCAAGTGR FLEMMARTLQ MKLPEMSELG LDWHNDVTIS SMCTVFAESE VVSLIARSTA
PADIIHGLNK SVAGKTAALA RRTGGVAPFM MTGGVARNRG VVKELETALK APVEVSEYSQ
LCGSLGAALF ALEKMGVKL
//
