ID A0A367IKE8_RHIST Unreviewed; 323 AA.
AC A0A367IKE8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Mitofusin {ECO:0000313|EMBL:RCH78103.1};
DE Flags: Fragment;
GN Name=FZO1_2 {ECO:0000313|EMBL:RCH78103.1};
GN ORFNames=CU098_002377 {ECO:0000313|EMBL:RCH78103.1};
OS Rhizopus stolonifer (Rhizopus nigricans).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=4846 {ECO:0000313|EMBL:RCH78103.1, ECO:0000313|Proteomes:UP000253551};
RN [1] {ECO:0000313|EMBL:RCH78103.1, ECO:0000313|Proteomes:UP000253551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSU 92-RS-03 {ECO:0000313|EMBL:RCH78103.1,
RC ECO:0000313|Proteomes:UP000253551};
RX PubMed=29674435; DOI=10.1534/g3.118.200235;
RA Gryganskyi A.P., Golan J., Dolatabadi S., Mondo S., Robb S., Idnurm A.,
RA Muszewska A., Steczkiewicz K., Masonjones S., Liao H.L., Gajdeczka M.T.,
RA Anike F., Vuek A., Anishchenko I.M., Voigt K., de Hoog G.S., Smith M.E.,
RA Heitman J., Vilgalys R., Stajich J.E.;
RT "Phylogenetic and Phylogenomic Definition of Rhizopus Species.";
RL G3 (Bethesda) 8:2007-2018(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001270};
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004374}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCH78103.1}.
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DR EMBL; PJQM01007495; RCH78103.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367IKE8; -.
DR STRING; 4846.A0A367IKE8; -.
DR EnsemblFungi; RCH78103; RCH78103; CU098_002377.
DR Proteomes; UP000253551; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027094; Mitofusin_fam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10465; TRANSMEMBRANE GTPASE FZO1; 1.
DR PANTHER; PTHR10465:SF0; TRANSMEMBRANE GTPASE MARF-RELATED; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000253551}.
FT DOMAIN 166..323
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT NON_TER 323
FT /evidence="ECO:0000313|EMBL:RCH78103.1"
SQ SEQUENCE 323 AA; 35891 MW; 27D5D9728AC6812B CRC64;
MTDPAFGSSF LASKASVRRN SASNIDTIQT TFESPTPSPT TTAARTHQHR LNAAQEQRTY
QDSCKRLISH IISVIDLCGD LSKGNKDKHP MYYPTENSAI LEATRSTAFQ DKSVFSSNLN
ILGLDLKMGH TSTDLSALES QSITNLLSDR IDISSRHLKR LQSRVADTSS KVLVTGDLNS
GKSTFVNALL KRNILPADQQ PCTSVFCEVL DAMLNDGLEQ VHAIPCVEKY NRLNPDTYHV
VEMRHLYKII TKDFEHYKML KIYANDARNM QESLLHNGVV DIALIDSPGL NTDSVKTTAV
FARQEEIDVV VFVVSAENHF TLS
//
