ID A0A367JB77_RHIST Unreviewed; 706 AA.
AC A0A367JB77;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA repair protein rad4 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=CU098_003031 {ECO:0000313|EMBL:RCH87190.1};
OS Rhizopus stolonifer (Rhizopus nigricans).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=4846 {ECO:0000313|EMBL:RCH87190.1, ECO:0000313|Proteomes:UP000253551};
RN [1] {ECO:0000313|EMBL:RCH87190.1, ECO:0000313|Proteomes:UP000253551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSU 92-RS-03 {ECO:0000313|EMBL:RCH87190.1,
RC ECO:0000313|Proteomes:UP000253551};
RX PubMed=29674435; DOI=10.1534/g3.118.200235;
RA Gryganskyi A.P., Golan J., Dolatabadi S., Mondo S., Robb S., Idnurm A.,
RA Muszewska A., Steczkiewicz K., Masonjones S., Liao H.L., Gajdeczka M.T.,
RA Anike F., Vuek A., Anishchenko I.M., Voigt K., de Hoog G.S., Smith M.E.,
RA Heitman J., Vilgalys R., Stajich J.E.;
RT "Phylogenetic and Phylogenomic Definition of Rhizopus Species.";
RL G3 (Bethesda) 8:2007-2018(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCH87190.1}.
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DR EMBL; PJQM01003769; RCH87190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367JB77; -.
DR STRING; 4846.A0A367JB77; -.
DR EnsemblFungi; RCH87190; RCH87190; CU098_003031.
DR Proteomes; UP000253551; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000253551}.
FT DOMAIN 437..488
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 490..552
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 559..633
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..77
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..687
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RCH87190.1"
SQ SEQUENCE 706 AA; 81748 MW; BA98BF820A28DF0F CRC64;
DNESQGKDVQ KKVVKTSPLV ESSRSKRKIQ DSQKDFESRP SKKGKEKEVL EEPVENDDAM
TFENDIEDDD DEEEEEFDWE TVELPQTTTN EQDQETQVYK DVEITFEAPR AILKKSRWEV
EYQRNLREWI HNAHVLTLVS HYTLRNRWCS SEKAQSQCLK IIPKDIKNHN PPEPMIRLKL
LLKWWQEYFS ITGLGLQTHP YSDFGNIKFS VLQKMMTESS DRIDSLDDFL KLLLTKEGTS
DVYSELFVAI LRACGYDTRL VCSLQPLPYK IPPEKKSEKD ESRESQDEKS DLLFQFRTPT
KTHIDQNLQL KQKNAKPPMV WAEVYCHKSK RWICVDPLRE IVDKPALMEP AALNRGNQLS
FVLALDEKRK RCITDVTRRY TSNMDRAVRL RGRPITKREQ AAGMKPWFEV FMETVCYKPK
MGEREELELQ DLDRQETKEK MPTSIGAFKN NSSYVLERHL KKFEILYPKE PILGSIKGEK
IYPRQCVKVV STADVYRKQG REIIKGEQPV KMVKTAATTI EKKRINEMAK QDGQEAMTPC
YGEWQTQKII PDPIIDGKVT KNSYGNIDLF TPEMLPAGGV HIPIKGIGKI AKKLGVDYAD
AVTGFEFVKM RSVPIIEGIV IAKEFQYVIM EALEEQEQNE AIKAIEKQEK EVHLRWRKLI
KSLLIKARVD DEYGKEKESK GNEDMWATFN KDADAGGGGF LPEDDL
//
