ID A0A367K2Z7_RHIAZ Unreviewed; 745 AA.
AC A0A367K2Z7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=CU097_011775 {ECO:0000313|EMBL:RCH96261.1};
OS Rhizopus azygosporus (Rhizopus microsporus var. azygosporus).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=86630 {ECO:0000313|EMBL:RCH96261.1, ECO:0000313|Proteomes:UP000252139};
RN [1] {ECO:0000313|EMBL:RCH96261.1, ECO:0000313|Proteomes:UP000252139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 357.93 {ECO:0000313|EMBL:RCH96261.1,
RC ECO:0000313|Proteomes:UP000252139};
RX PubMed=29674435; DOI=10.1534/g3.118.200235;
RA Gryganskyi A.P., Golan J., Dolatabadi S., Mondo S., Robb S., Idnurm A.,
RA Muszewska A., Steczkiewicz K., Masonjones S., Liao H.L., Gajdeczka M.T.,
RA Anike F., Vuek A., Anishchenko I.M., Voigt K., de Hoog G.S., Smith M.E.,
RA Heitman J., Vilgalys R., Stajich J.E.;
RT "Phylogenetic and Phylogenomic Definition of Rhizopus Species.";
RL G3 (Bethesda) 8:2007-2018(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RCH96261.1}.
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DR EMBL; PJQL01000386; RCH96261.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A367K2Z7; -.
DR STRING; 86630.A0A367K2Z7; -.
DR Proteomes; UP000252139; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF10; BETA-GLUCOSIDASE F-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023001};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023001};
KW Reference proteome {ECO:0000313|Proteomes:UP000252139};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..745
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016900218"
FT DOMAIN 645..714
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 745 AA; 80823 MW; 670C5EE0634517FE CRC64;
MHIPSIFIAT IIGLLAVSAS AKPTEPKINL RSWDEAYMMA KALVSKMSLE QKVNITTGIG
FGSGHCEGNT FAISNPDFPS LCLQDSPLGI QLAYNVTSGV AGINAAASFD RKAIRDRGVY
MGQEFRGRGI NVQLGPAMNF MRSPESGRGW ESGGEDPFLT GVLAEETVLG IQSQGVIATA
KHYILNDQEL HRNTESSDID ERTLHEIYIW PFARAVEAGV GSIMCSYNQI NGIFACENDY
LLNTVLKGEL GFKGFVQSDW LATMSTVDSA NHGLDMNMPG NITIGSSGSY FGKNLTDAVH
AKKVPESRVT DMATRIVAAW YKLGQDKDFP KTTLDSFHLN KVSYVNVQSD HYKLVRSMGA
ASTVLLRNSG ILPLNKSVKN VAFVGSDAAV NPDGINSCFA HSCNKGTLAQ GWGSGTAIFP
YLVDPIIGFR NALGKDVKFT KSLDDWDLDA AAAAAKDADV AFVFSNADSG EGFIVVDGNT
GDRNNLSLWN NGDNLIKAVA DSNKNTVVVI HSVGPVLMPW IDHPNIKAVV WPGLPGQESG
NSLADVVTGK VNPSGRLPYT IAKKVSDYPI KPDPAHNVVY KEKLLMGYKW FDANNVTPLF
PFGHGLSYTN FTYSDLTVKV EASGKPTKVT VTVTVKNTGH LDGAEIPQLY LSFPESANEP
PKLLRGFEKV FIKANKEQEV KFELTSTELS IWDIDSKSWV VPSGKFIVHV GASSRDIRQS
ADFIFSSRVQ GPVLDRFVRL ALSLL
//
