ID   A0A367KHZ3_RHIST        Unreviewed;      1282 AA.
AC   A0A367KHZ3;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN   ORFNames=CU098_005512 {ECO:0000313|EMBL:RCI01761.1};
OS   Rhizopus stolonifer (Rhizopus nigricans).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX   NCBI_TaxID=4846 {ECO:0000313|EMBL:RCI01761.1, ECO:0000313|Proteomes:UP000253551};
RN   [1] {ECO:0000313|EMBL:RCI01761.1, ECO:0000313|Proteomes:UP000253551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LSU 92-RS-03 {ECO:0000313|EMBL:RCI01761.1,
RC   ECO:0000313|Proteomes:UP000253551};
RX   PubMed=29674435; DOI=10.1534/g3.118.200235;
RA   Gryganskyi A.P., Golan J., Dolatabadi S., Mondo S., Robb S., Idnurm A.,
RA   Muszewska A., Steczkiewicz K., Masonjones S., Liao H.L., Gajdeczka M.T.,
RA   Anike F., Vuek A., Anishchenko I.M., Voigt K., de Hoog G.S., Smith M.E.,
RA   Heitman J., Vilgalys R., Stajich J.E.;
RT   "Phylogenetic and Phylogenomic Definition of Rhizopus Species.";
RL   G3 (Bethesda) 8:2007-2018(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RCI01761.1}.
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DR   EMBL; PJQM01001675; RCI01761.1; -; Genomic_DNA.
DR   STRING; 4846.A0A367KHZ3; -.
DR   EnsemblFungi; RCI01761; RCI01761; CU098_005512.
DR   Proteomes; UP000253551; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039930; RALGAPB.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR046859; RGPA/RALGAPB_N.
DR   PANTHER; PTHR21344:SF1; RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA; 1.
DR   PANTHER; PTHR21344; UNCHARACTERIZED; 1.
DR   Pfam; PF20412; RALGAPB_N; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253551}.
FT   DOMAIN          1049..1259
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          159..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          748..803
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        770..798
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1282 AA;  144820 MW;  ED6F7C56B87D78AE CRC64;
     MFLDWIAQLQ TNILGSLPLS IRRVLISEIT TYLHPPPGKQ APDPSIFCSP AHIKWFMEVI
     GQGFNLPLED MAITNDDVEI YSRWLFEPQT RPAAVMKEGL EQEFYQIIFH QFSLLFQPRI
     ARNSIVPTQD KSHLLPPKPS SSFHINMLPV GAHSTIVPIT FNPPTSSSTP TSNTNANSGT
     TNAASTATSG LQSNPNNSNS QATLKETLSQ LVQRHIELCK KSLRVFAMAG RTLKMSTDTW
     SVLLKVMLGI TDYLLKEPTG ESSTMGVMNM GDELCDSLLQ VLFELWLRSN TMDVEMWDIL
     KSCFGRWIHR PKAIQQWSST SLAITKRIQH LVYGDQENAE GVFVSGPNVK LDLPNEFTYY
     AWHRIIYLIP HPLQLPSHNF TLAMLGIGNL VDTLNSAIET TDTMASPDGN TLLNMFGTYL
     FDAASKSNQA DTEAQRGCAE SLATLCRIFC KPQRRQPFLR TYIERFYAAL MTGLKSEACL
     PTILLSCTEL FATDLEGVRM LVPDFISAIK MVLPKLTFEY KTNVSVDNLR LAAIKVLSTI
     MCLPNHFDKV ELAKSSWDSS DVSLESVSVI RVLYASPAEG NSDKPCLSLK FYILEVLLKS
     LRTETSSYNM RYILHLINVY VIEDVPFCPG LVGTILTMQL PADVTLVAFD VLMDFVDLYD
     FVKRDSKNVA RELVLALSRY VDTLITAGKL AQTYPLIVQA YDCMIKWILI SQWIIDDRDC
     YKAVIATLSK GITIFDREAA NLAAPTEPVN VEKKKRRETG FPPTKQLFQL PPRVNKTSHH
     HTDQTQQPSS SNPNSRNSSA VRKKEEVAVR MAAEYCMSQF VNHLGQFISP DNKKILEESI
     DDVAQLKQLL ASEEAEYSIR SFLIDKRTVL TLIDTTKTSD DNVPAITVII RDTTGKYVWS
     MEARYKEHVP QNIHTASLPP STTQQSLGDN VFLKPAEARK IQKPVTVPTA TAVNEKELPS
     LDKVFVPESE SWQQWEALKS LIDRQLMNDT RKTESKFLHE YQISPTRFNI DTDTPRGFRL
     FLSQIGFLLP ENRHHITPLH LTDSVITEME TLDMLNERDC ISISAYYAVS GNVNLEELIE
     TPPPLSQQFL QFMNCLGWPV DIAEHKGYKG KLDATICAKI PYYSDRTVEF VVNVPYFLKS
     SPSSEQTLSE IYQRVSSDDH VCVVWIEDVT EYKKLAKLIK TSSATQSKTM VYIFISPLKH
     SADSLYWIFG PLVDGIVVSR HALGSMVRST SISAHQACRV VTDTYTRPYV IRREYIEEMA
     HRHRVKLPLS EFYTDVFTEK TN
//